Entity Details

Primary name PRTN3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP24158
EntryNamePRTN3_HUMAN
FullNameMyeloblastin
TaxID9606
Evidenceevidence at protein level
Length256
SequenceStatuscomplete
DateCreated1992-03-01
DateModified2021-06-02

Ontological Relatives

GenesPRTN3

GO terms

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GOName
GO:0004252 serine-type endopeptidase activity
GO:0005102 signaling receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006508 proteolysis
GO:0006509 membrane protein ectodomain proteolysis
GO:0006909 phagocytosis
GO:0007596 blood coagulation
GO:0008236 serine-type peptidase activity
GO:0008284 positive regulation of cell population proliferation
GO:0019221 cytokine-mediated signaling pathway
GO:0019730 antimicrobial humoral response
GO:0019899 enzyme binding
GO:0030574 collagen catabolic process
GO:0035578 azurophil granule lumen
GO:0043231 intracellular membrane-bounded organelle
GO:0043312 neutrophil degranulation
GO:0043547 positive regulation of GTPase activity
GO:0044853 plasma membrane raft
GO:0045217 cell-cell junction maintenance
GO:0050765 negative regulation of phagocytosis
GO:0070062 extracellular exosome
GO:0072672 neutrophil extravasation
GO:0097029 mature conventional dendritic cell differentiation

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasmic granule
Membrane raft
Secreted

Domains

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DomainNameCategoryType
IPR001254 Serine proteases, trypsin domainDomainDomain
IPR001314 Peptidase S1A, chymotrypsin familyFamilyFamily
IPR009003 Peptidase S1, PA clanFamilyHomologous superfamily
IPR018114 Serine proteases, trypsin family, histidine active siteSiteActive site
IPR033116 Serine proteases, trypsin family, serine active siteSiteActive site
IPR043504 Peptidase S1, PA clan, chymotrypsin-like foldFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB05161 ElafinDrugbanksmall molecule