Entity Details

Primary name DMB_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP28068
EntryNameDMB_HUMAN
FullNameHLA class II histocompatibility antigen, DM beta chain
TaxID9606
Evidenceevidence at protein level
Length263
SequenceStatuscomplete
DateCreated1992-08-01
DateModified2021-06-02

Ontological Relatives

GenesHLA-DMB

GO terms

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GOName
GO:0002250 adaptive immune response
GO:0002399 MHC class II protein complex assembly
GO:0002503 peptide antigen assembly with MHC class II protein complex
GO:0005765 lysosomal membrane
GO:0016021 integral component of membrane
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0023026 MHC class II protein complex binding
GO:0031902 late endosome membrane
GO:0042102 positive regulation of T cell proliferation
GO:0042613 MHC class II protein complex
GO:0043231 intracellular membrane-bounded organelle
GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

Subcellular Location

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Subcellular Location
Late endosome membrane
Lysosome membrane

Domains

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DomainNameCategoryType
IPR000353 MHC class II, beta chain, N-terminalDomainDomain
IPR003006 Immunoglobulin/major histocompatibility complex, conserved siteSiteConserved site
IPR003597 Immunoglobulin C1-setDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR011162 MHC classes I/II-like antigen recognition proteinFamilyHomologous superfamily
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR014745 MHC class II, alpha/beta chain, N-terminalFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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