Entity Details

Primary name GSTM2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP28161
EntryNameGSTM2_HUMAN
FullNameGlutathione S-transferase Mu 2
TaxID9606
Evidenceevidence at protein level
Length218
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GenesGSTM2

GO terms

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GOName
GO:0004364 glutathione transferase activity
GO:0004602 glutathione peroxidase activity
GO:0005102 signaling receptor binding
GO:0005504 fatty acid binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006749 glutathione metabolic process
GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
GO:0016529 sarcoplasmic reticulum
GO:0018916 nitrobenzene metabolic process
GO:0019899 enzyme binding
GO:0042178 xenobiotic catabolic process
GO:0042803 protein homodimerization activity
GO:0043295 glutathione binding
GO:0043651 linoleic acid metabolic process
GO:0045171 intercellular bridge
GO:0051122 hepoxilin biosynthetic process
GO:0055119 relaxation of cardiac muscle
GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity
GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity
GO:0070062 extracellular exosome
GO:0070458 cellular detoxification of nitrogen compound
GO:0071313 cellular response to caffeine
GO:1901687 glutathione derivative biosynthetic process

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR003081 Glutathione S-transferase, Mu classFamilyFamily
IPR004045 Glutathione S-transferase, N-terminalDomainDomain
IPR004046 Glutathione S-transferase, C-terminalDomainDomain
IPR010987 Glutathione S-transferase, C-terminal-likeDomainDomain
IPR036249 Thioredoxin-like superfamilyFamilyHomologous superfamily
IPR036282 Glutathione S-transferase, C-terminal domain superfamilyFamilyHomologous superfamily
IPR040079 Glutathione Transferase familyFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00143 GlutathioneDrugbanksmall molecule
DB02458 S-(2,4-dinitrophenyl)glutathioneDrugbanksmall molecule
DB03310 Glutathione disulfideDrugbanksmall molecule
DB04701 S-Methyl glutathioneDrugbanksmall molecule