Entity Details

Primary name DHB3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP37058
EntryNameDHB3_HUMAN
FullNameTestosterone 17-beta-dehydrogenase 3
TaxID9606
Evidenceevidence at protein level
Length310
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesHSD17B3

GO terms

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GOName
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0006694 steroid biosynthetic process
GO:0006702 androgen biosynthetic process
GO:0030539 male genitalia development
GO:0043231 intracellular membrane-bounded organelle
GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity
GO:0061370 testosterone biosynthetic process
GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity

Subcellular Location

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Subcellular Location
Endoplasmic reticulum

Domains

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DomainNameCategoryType
IPR002347 Short-chain dehydrogenase/reductase SDRFamilyFamily
IPR020904 Short-chain dehydrogenase/reductase, conserved siteSiteConserved site
IPR033281 Testosterone 17-beta-dehydrogenase 3FamilyFamily
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00157 NADHDrugbanksmall molecule