Entity Details

Primary name PPCE_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP48147
EntryNamePPCE_HUMAN
FullNameProlyl endopeptidase
TaxID9606
Evidenceevidence at protein level
Length710
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesPREP

GO terms

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GOName
GO:0004175 endopeptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006508 proteolysis
GO:0008236 serine-type peptidase activity
GO:0016020 membrane
GO:0070012 oligopeptidase activity

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domainDomainDomain
IPR002470 Peptidase S9A, prolyl oligopeptidaseFamilyFamily
IPR002471 Peptidase S9, serine active siteSiteActive site
IPR023302 Peptidase S9A, N-terminal domainDomainDomain
IPR029058 Alpha/Beta hydrolase foldFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00107 OxytocinDrugbankbiotech
DB01684 1-Hydroxy-1-Thio-GlycerolDrugbanksmall molecule
DB03382 S-oxy-L-cysteineDrugbanksmall molecule
DB03535 Z-Pro-ProlinalDrugbanksmall molecule
DB03864 MonothioglycerolDrugbanksmall molecule
DB07148 (6S)-1-chloro-3-[(4-fluorobenzyl)oxy]-6-(pyrrolidin-1-ylcarbonyl)pyrrolo[1,2-a]pyrazin-4(6H)-oneDrugbanksmall molecule
DB08738 1-{3-oxo-3-[(2S)-2-(pyrrolidin-1-ylcarbonyl)pyrrolidin-1-yl]propyl}-3-phenylquinoxalin-2(1H)-oneDrugbanksmall molecule
DB08739 2-{3-[(2S)-4,4-difluoro-2-(pyrrolidin-1-ylcarbonyl)pyrrolidin-1-yl]-3-oxopropyl}-isoindole-1,3(2H)-dioneDrugbanksmall molecule