Entity Details

Primary name GIPR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP48546
EntryNameGIPR_HUMAN
FullNameGastric inhibitory polypeptide receptor
TaxID9606
Evidenceevidence at protein level
Length466
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesGIPR

GO terms

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GOName
GO:0002029 desensitization of G protein-coupled receptor signaling pathway
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0004888 transmembrane signaling receptor activity
GO:0005886 plasma membrane
GO:0006091 generation of precursor metabolites and energy
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO:0007190 activation of adenylate cyclase activity
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007584 response to nutrient
GO:0008528 G protein-coupled peptide receptor activity
GO:0009749 response to glucose
GO:0016021 integral component of membrane
GO:0016519 gastric inhibitory peptide receptor activity
GO:0017046 peptide hormone binding
GO:0031018 endocrine pancreas development
GO:0032024 positive regulation of insulin secretion
GO:0043950 positive regulation of cAMP-mediated signaling
GO:0048678 response to axon injury
GO:0050796 regulation of insulin secretion
GO:0051592 response to calcium ion
GO:0070542 response to fatty acid

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000832 GPCR, family 2, secretin-likeFamilyFamily
IPR001749 GPCR, family 2, gastric inhibitory polypeptide receptorFamilyFamily
IPR001879 GPCR, family 2, extracellular hormone receptor domainDomainDomain
IPR017981 GPCR, family 2-likeDomainDomain
IPR017983 GPCR, family 2, secretin-like, conserved siteSiteConserved site
IPR036445 GPCR family 2, extracellular hormone receptor domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions