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Entity Details
Primary name
TTPA_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
P49638
EntryName
TTPA_HUMAN
FullName
Alpha-tocopherol transfer protein
TaxID
9606
Evidence
evidence at protein level
Length
278
SequenceStatus
complete
DateCreated
1996-02-01
DateModified
2021-06-02
Ontological Relatives
Genes
TTPA
GO terms
Show/Hide Table
GO
Name
GO:0005546
phosphatidylinositol-4,5-bisphosphate binding
GO:0005770
late endosome
GO:0005829
cytosol
GO:0006629
lipid metabolic process
GO:0007584
response to nutrient
GO:0008431
vitamin E binding
GO:0009268
response to pH
GO:0032502
developmental process
GO:0042360
vitamin E metabolic process
GO:0043325
phosphatidylinositol-3,4-bisphosphate binding
GO:0051180
vitamin transport
GO:0051452
intracellular pH reduction
GO:0060548
negative regulation of cell death
GO:0120009
intermembrane lipid transfer
GO:0120013
lipid transfer activity
GO:1902936
phosphatidylinositol bisphosphate binding
Subcellular Location
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Subcellular Location
Cytoplasm
Domains
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Domain
Name
Category
Type
IPR001251
CRAL-TRIO lipid binding domain
Domain
Domain
IPR011074
CRAL/TRIO, N-terminal domain
Domain
Domain
IPR036273
CRAL/TRIO, N-terminal domain superfamily
Family
Homologous superfamily
IPR036865
CRAL-TRIO lipid binding domain superfamily
Family
Homologous superfamily
Diseases
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Drugs
Show/Hide Table
Drug
Name
Source
Type
DB00163
Vitamin E
Drugbank
small molecule
DB02080
1-{2-[2-(2-Methoxyethoxy)Ethoxy]Ethoxy}-4-(1,1,3,3-Tetramethylbutyl)Benzene
Drugbank
small molecule
DB11251
Tocopherol
Swissprot
small molecule
DB11635
Tocofersolan
Drugbank
small molecule
DB14001
alpha-Tocopherol succinate
Drugbank
small molecule
DB14002
D-alpha-Tocopherol acetate
Drugbank
small molecule
DB14003
alpha-Tocopherol acetate
Swissprot
small molecule
Interactions
48 interactions
Interactor
Partner
Sources
Publications
Link
TTPA_HUMAN
F1142_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
RPRM_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
MAL2_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
NDUA7_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
PYRD_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
JOS2_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
REEP2_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
DHB11_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
BIRC7_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
ARFP2_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
KRA23_HUMAN
BioGRID
32296183
details
TTPA_HUMAN
KR122_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
APOA5_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
APOC2_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
FM25A_HUMAN
BioGRID
32296183
details
TTPA_HUMAN
FADS6_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
FM25C_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
COQ3_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
FKBP7_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
ARM12_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
CISD2_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
CKLF5_HUMAN
BioGRID, IntAct
25416956
32296183
details
TTPA_HUMAN
SNG3_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
SAR1A_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
PEX12_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
ATRAP_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
FM25G_HUMAN
BioGRID
32296183
details
TTPA_HUMAN
KR123_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
KRA24_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
GOGA2_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
DG2L6_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
LEUTX_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
SCAM5_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
A4_HUMAN
BioGRID
21832049
details
TTPA_HUMAN
CRTP1_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
RDHE2_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
FGF14_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
THAP4_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
KR107_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
SCAM1_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
CKLF4_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
TPD52_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
NT2NC_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
MRM1_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
SHLB1_HUMAN
IntAct
32814053
details
TTPA_HUMAN
NT2NA_HUMAN
BioGRID
32296183
details
TTPA_HUMAN
S35E3_HUMAN
BioGRID, IntAct
32296183
details
TTPA_HUMAN
MGMT_HUMAN
BioGRID
16226712
details
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