Entity Details

Primary name GPC3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP51654
EntryNameGPC3_HUMAN
FullNameGlypican-3
TaxID9606
Evidenceevidence at protein level
Length580
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesGPC3

GO terms

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GOName
GO:0001523 retinoid metabolic process
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0005788 endoplasmic reticulum lumen
GO:0005796 Golgi lumen
GO:0005886 plasma membrane
GO:0006024 glycosaminoglycan biosynthetic process
GO:0006027 glycosaminoglycan catabolic process
GO:0009617 response to bacterium
GO:0009653 anatomical structure morphogenesis
GO:0009948 anterior/posterior axis specification
GO:0009986 cell surface
GO:0010171 body morphogenesis
GO:0010466 negative regulation of peptidase activity
GO:0016477 cell migration
GO:0030282 bone mineralization
GO:0030316 osteoclast differentiation
GO:0030324 lung development
GO:0030513 positive regulation of BMP signaling pathway
GO:0031226 intrinsic component of plasma membrane
GO:0035116 embryonic hindlimb morphogenesis
GO:0042074 cell migration involved in gastrulation
GO:0043202 lysosomal lumen
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
GO:0045732 positive regulation of protein catabolic process
GO:0045807 positive regulation of endocytosis
GO:0045879 negative regulation of smoothened signaling pathway
GO:0045880 positive regulation of smoothened signaling pathway
GO:0045926 negative regulation of growth
GO:0046326 positive regulation of glucose import
GO:0046658 anchored component of plasma membrane
GO:0050680 negative regulation of epithelial cell proliferation
GO:0060422 peptidyl-dipeptidase inhibitor activity
GO:0060828 regulation of canonical Wnt signaling pathway
GO:0060976 coronary vasculature development
GO:0062023 collagen-containing extracellular matrix
GO:0072111 cell proliferation involved in kidney development
GO:0072138 mesenchymal cell proliferation involved in ureteric bud development
GO:0072180 mesonephric duct morphogenesis
GO:0072203 cell proliferation involved in metanephros development
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:1905475 regulation of protein localization to membrane
GO:2000050 regulation of non-canonical Wnt signaling pathway
GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001863 GlypicanFamilyFamily
IPR015501 Glypican-3FamilyFamily
IPR019803 Glypican, conserved siteSiteConserved site

Diseases

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