Entity Details

Primary name 2ABA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP63151
EntryName2ABA_HUMAN
FullNameSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform
TaxID9606
Evidenceevidence at protein level
Length447
SequenceStatuscomplete
DateCreated2004-09-27
DateModified2021-06-02

Ontological Relatives

GenesPPP2R2A

GO terms

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GOName
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000159 protein phosphatase type 2A complex
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006470 protein dephosphorylation
GO:0007084 mitotic nuclear membrane reassembly
GO:0019888 protein phosphatase regulator activity
GO:0043278 response to morphine
GO:0044877 protein-containing complex binding
GO:0048156 tau protein binding
GO:0051721 protein phosphatase 2A binding
GO:0070262 peptidyl-serine dephosphorylation
GO:0098978 glutamatergic synapse

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000009 Protein phosphatase 2A regulatory subunit PR55FamilyFamily
IPR001680 WD40 repeatRepeatRepeat
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR018067 Protein phosphatase 2A regulatory subunit PR55, conserved siteSiteConserved site
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB02506 2,6,8-Trimethyl-3-Amino-9-Benzyl-9-Methoxynonanoic AcidDrugbanksmall molecule

Interactions

49 interactions

InteractorPartnerSourcesPublicationsLink
2ABA_HUMAN2AAA_HUMANBioGRID, DIP, HPRD, IntAct, MINT12370081 15761952 17245430 17529992 17540176 17632056 18782753 19156129 19293187 19915589 20711181 22939629 23443559 26344197 26496610 27173435 28330616 32950569 unassigned1312 details
2ABA_HUMAN2AAB_HUMANBioGRID, HPRD, IntAct12370081 1328247 17540176 19156129 22939629 26344197 26496610 28330616 details
2ABA_HUMANPP2AA_HUMANBioGRID, DIP, HPRD, IntAct, MINT10191253 1328247 18782753 19156129 19915589 20711181 22939629 26344197 26496610 27880917 28330616 32950569 details
2ABA_HUMANLRP1B_HUMANIntAct32814053 details
2ABA_HUMANNEDD8_HUMANIntAct32814053 details
2ABA_HUMANA4_HUMANIntAct32814053 details
2ABA_HUMANMTOR_HUMANBioGRID10200280 details
2ABA_HUMANRRN3_HUMANBioGRID15004009 details
2ABA_HUMANTGFR1_HUMANBioGRID, HPRD9774674 details
2ABA_HUMANNOSIP_HUMANBioGRID25546391 details
2ABA_HUMANCBP_HUMANBioGRID28680062 details
2ABA_HUMANBRAF_HUMANBioGRID31015455 details
2ABA_HUMANAMOL2_HUMANBioGRID32950569 details
2ABA_HUMANCHK2_HUMANHPRD15380617 details
2ABA_HUMANP53_HUMANMINT17245430 details
2ABA_HUMANDAPK1_HUMANMINT20220139 details
2ABA_HUMANANKL2_HUMANIntAct22770216 details
2ABA_HUMANHDAC5_HUMANBioGRID, IntAct21081666 23752268 details
2ABA_HUMANFOXC2_HUMANBioGRID, IntAct23878394 26496610 details
2ABA_HUMANCDCA4_HUMANBioGRID, IntAct19156129 26496610 28330616 details
2ABA_HUMAN2ABD_HUMANBioGRID, IntAct19156129 28330616 28514442 details
2ABA_HUMANMTREX_HUMANBioGRID, IntAct19156129 28330616 details
2ABA_HUMANLRRK2_HUMANIntAct26894577 31046837 details
2ABA_HUMAN4EBP1_HUMANBioGRID16899564 details
2ABA_HUMANKS6B1_HUMANBioGRID10200280 16899564 details
2ABA_HUMANMLH1_HUMANBioGRID17148452 details
2ABA_HUMANTCPE_HUMANBioGRID19156129 details
2ABA_HUMANTCPQ_HUMANBioGRID19156129 details
2ABA_HUMANTCPB_HUMANBioGRID19156129 details
2ABA_HUMANTCPD_HUMANBioGRID19156129 details
2ABA_HUMANTCPH_HUMANBioGRID19156129 details
2ABA_HUMANTBA4A_HUMANBioGRID19156129 details
2ABA_HUMANTCPG_HUMANBioGRID19156129 details
2ABA_HUMANTCPA_HUMANBioGRID19156129 details
2ABA_HUMANFABP5_HUMANBioGRID19156129 details
2ABA_HUMANDESP_HUMANBioGRID19156129 details
2ABA_HUMANDSG1_HUMANBioGRID19156129 details
2ABA_HUMANTCPZ_HUMANBioGRID19156129 details
2ABA_HUMANG3P_HUMANBioGRID19156129 details
2ABA_HUMANPTN14_HUMANBioGRID22948661 details
2ABA_HUMANGRB2_HUMANBioGRID21706016 details
2ABA_HUMANEGFR_HUMANBioGRID23956138 details
2ABA_HUMANABCE1_HUMANBioGRID25659154 details
2ABA_HUMANCA131_HUMANBioGRID26472760 details
2ABA_HUMANDERL1_HUMANBioGRID28137758 details
2ABA_HUMANANDR_HUMANBioGRID28611094 details
2ABA_HUMANNMDE4_HUMANHPRD10862698 details
2ABA_HUMANSTRN3_HUMANHPRD10681496 details
2ABA_HUMANNMDZ1_HUMANHPRD10862698 details