Entity Details

Primary name ASIC1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP78348
EntryNameASIC1_HUMAN
FullNameAcid-sensing ion channel 1
TaxID9606
Evidenceevidence at protein level
Length528
SequenceStatuscomplete
DateCreated2001-12-05
DateModified2021-06-02

Ontological Relatives

GenesASIC1

GO terms

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GOName
GO:0001662 behavioral fear response
GO:0001975 response to amphetamine
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006814 sodium ion transport
GO:0007165 signal transduction
GO:0007613 memory
GO:0008306 associative learning
GO:0009268 response to pH
GO:0009986 cell surface
GO:0010447 response to acidic pH
GO:0015280 ligand-gated sodium channel activity
GO:0022839 ion gated channel activity
GO:0034220 ion transmembrane transport
GO:0035725 sodium ion transmembrane transport
GO:0042391 regulation of membrane potential
GO:0044736 acid-sensing ion channel activity
GO:0045202 synapse
GO:0046929 negative regulation of neurotransmitter secretion
GO:0050915 sensory perception of sour taste
GO:0070207 protein homotrimerization
GO:0070588 calcium ion transmembrane transport
GO:0071467 cellular response to pH

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001873 Epithelial sodium channelFamilyFamily
IPR004724 Epithelial sodium channel, chordatesFamilyFamily
IPR020903 Epithelial sodium channel, conserved siteSiteConserved site

Diseases

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Drugs

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DrugNameSourceType
DB00586 DiclofenacDrugbanksmall molecule
DB00594 AmilorideDrugbanksmall molecule