Entity Details

Primary name ID3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ02535
EntryNameID3_HUMAN
FullNameDNA-binding protein inhibitor ID-3
TaxID9606
Evidenceevidence at protein level
Length119
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GenesID3

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001656 metanephros development
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006275 regulation of DNA replication
GO:0007275 multicellular organism development
GO:0007417 central nervous system development
GO:0007507 heart development
GO:0007517 muscle organ development
GO:0008134 transcription factor binding
GO:0009611 response to wounding
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0019904 protein domain specific binding
GO:0030154 cell differentiation
GO:0030182 neuron differentiation
GO:0030855 epithelial cell differentiation
GO:0030903 notochord development
GO:0032922 circadian regulation of gene expression
GO:0042476 odontogenesis
GO:0043065 positive regulation of apoptotic process
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0045662 negative regulation of myoblast differentiation
GO:0045668 negative regulation of osteoblast differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0046983 protein dimerization activity
GO:0051726 regulation of cell cycle
GO:0072750 cellular response to leptomycin B
GO:0140416 transcription regulator inhibitor activity
GO:1901707 leptomycin B binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR026052 DNA-binding protein inhibitorFamilyFamily
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

56 interactions

InteractorPartnerSourcesPublicationsLink
ID3_HUMANTSC1_HUMANIntAct17355907 details
ID3_HUMANATF3_HUMANBioGRID, IntAct18255255 details
ID3_HUMANCNOT3_HUMANBioGRID, IntAct18255255 details
ID3_HUMANCSK_HUMANBioGRID, IntAct18255255 details
ID3_HUMANFHL2_HUMANBioGRID, IntAct18255255 32296183 details
ID3_HUMANID3_HUMANBioGRID, HPRD, IntAct18255255 8645731 details
ID3_HUMANRND1_HUMANBioGRID, IntAct18255255 details
ID3_HUMANPUF60_HUMANBioGRID, IntAct18255255 details
ID3_HUMANMLX_HUMANBioGRID, IntAct18255255 details
ID3_HUMANZNF3_HUMANBioGRID, IntAct18255255 details
ID3_HUMANZN408_HUMANBioGRID, IntAct18255255 details
ID3_HUMANZN626_HUMANBioGRID, IntAct18255255 details
ID3_HUMANTFE2_HUMANBioGRID, HPRD, IntAct10915743 22354994 25416956 32296183 8759016 9242638 9525934 details
ID3_HUMANITF2_HUMANBioGRID, HPRD, IntAct, MINT11591653 25416956 25609649 28514442 32296183 8999959 9242638 details
ID3_HUMANHTF4_HUMANBioGRID, HPRD, IntAct20211142 25416956 31515488 32296183 9242638 details
ID3_HUMANF74A1_HUMANIntAct25416956 details
ID3_HUMANLMO4_HUMANBioGRID, IntAct32296183 details
ID3_HUMANFRS3_HUMANBioGRID, IntAct32296183 details
ID3_HUMANCREB5_HUMANBioGRID, IntAct32296183 details
ID3_HUMANSDCB1_HUMANBioGRID, IntAct32296183 details
ID3_HUMANHXA1_HUMANBioGRID, IntAct32296183 details
ID3_HUMANMSGN1_HUMANBioGRID, IntAct32296183 details
ID3_HUMANKAT5_HUMANBioGRID, IntAct32296183 details
ID3_HUMANMYF5_HUMANBioGRID, HPRD, IntAct32296183 9242638 details
ID3_HUMANCV039_HUMANBioGRID, IntAct32296183 details
ID3_HUMANGUCD1_HUMANBioGRID, IntAct32296183 details
ID3_HUMANKR261_HUMANBioGRID, IntAct32296183 details
ID3_HUMANPDLI5_HUMANDIP16549780 details
ID3_HUMANRAB7A_HUMANIntAct32814053 details
ID3_HUMANSPRE1_HUMANIntAct32814053 details
ID3_HUMANMTG8_HUMANHPRD, IntAct11591653 20211142 details
ID3_HUMANE2F4_HUMANBioGRID, IntAct20211142 details
ID3_HUMANPRD14_HUMANBioGRID, IntAct20211142 details
ID3_HUMANSAP30_HUMANBioGRID, IntAct20211142 details
ID3_HUMANNEMO_HUMANBioGRID, IntAct20211142 details
ID3_HUMANMTG8R_HUMANBioGRID, IntAct20211142 details
ID3_HUMANMYOD1_HUMANBioGRID, HPRD8759016 9242638 details
ID3_HUMANGATA4_HUMANBioGRID16556596 details
ID3_HUMANSMUF2_HUMANBioGRID21933340 details
ID3_HUMANCDK2_HUMANBioGRID, HPRD9372912 details
ID3_HUMANGBB2_HUMANBioGRID18255255 details
ID3_HUMANSRBP1_HUMANBioGRID, HPRD10585876 details
ID3_HUMANANS1A_HUMANBioGRID32296183 details
ID3_HUMANBOLA2_HUMANBioGRID32296183 details
ID3_HUMANTF2AY_HUMANHPRD8759016 details
ID3_HUMANID4_HUMANHPRD8759016 details
ID3_HUMANMYF6_HUMANHPRD9242638 details
ID3_HUMANHES1_HUMANHPRD11756408 details
ID3_HUMANMYOG_HUMANHPRD9242638 details
ID3_HUMANPAX5_HUMANBioGRID, HPRD12054881 details
ID3_HUMANNKX25_HUMANBioGRID16556596 details
ID3_HUMANSMAD1_HUMANBioGRID22884369 details
ID3_HUMANADDA_HUMANHPRD10585876 details
ID3_HUMANIF16_HUMANHPRD11940648 details
ID3_HUMANELK1_HUMANHPRD10022839 details
ID3_HUMANELK4_HUMANHPRD10022839 details