Entity Details

Primary name SRSF4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ08170
EntryNameSRSF4_HUMAN
FullNameSerine/arginine-rich splicing factor 4
TaxID9606
Evidenceevidence at protein level
Length494
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GenesSRSF4

GO terms

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GOName
GO:0000375 RNA splicing, via transesterification reactions
GO:0000398 mRNA splicing, via spliceosome
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006397 mRNA processing
GO:0006405 RNA export from nucleus
GO:0006406 mRNA export from nucleus
GO:0008380 RNA splicing
GO:0016607 nuclear speck
GO:0031124 mRNA 3'-end processing
GO:0032868 response to insulin
GO:0048025 negative regulation of mRNA splicing, via spliceosome
GO:1990825 sequence-specific mRNA binding

Subcellular Location

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Subcellular Location
Nucleus speckle

Domains

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DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR035585 Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1DomainDomain
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB11638 ArtenimolDrugbanksmall molecule

Interactions

33 interactions

InteractorPartnerSourcesPublicationsLink
SRSF4_HUMANHAP1_HUMANBioGRID, IntAct16169070 details
SRSF4_HUMANSRSF6_HUMANBioGRID, HPRD, IntAct16189514 31515488 details
SRSF4_HUMANRNPS1_HUMANBioGRID, IntAct, MINT17353931 22365833 details
SRSF4_HUMANTCAM1_HUMANBioGRID, IntAct21988832 details
SRSF4_HUMANHTSF1_HUMANBioGRID, MINT22365833 details
SRSF4_HUMANSRSF1_HUMANBioGRID, MINT22365833 24981860 details
SRSF4_HUMANSRRM2_HUMANBioGRID, MINT22365833 details
SRSF4_HUMANSNUT1_HUMANBioGRID, MINT22365833 details
SRSF4_HUMANPR38A_HUMANBioGRID, MINT22365833 details
SRSF4_HUMANSRSF2_HUMANBioGRID, MINT22365833 details
SRSF4_HUMANTRA2B_HUMANBioGRID, IntAct, MINT22365833 32296183 details
SRSF4_HUMANSRS10_HUMANBioGRID, MINT22365833 details
SRSF4_HUMANZDH17_HUMANBioGRID, IntAct24705354 details
SRSF4_HUMANJPH3_HUMANIntAct32814053 details
SRSF4_HUMANDYR1A_HUMANBioGRID14623875 details
SRSF4_HUMANPININ_HUMANBioGRID, HPRD14578391 details
SRSF4_HUMANSREK1_HUMANBioGRID, HPRD14559993 details
SRSF4_HUMANUBC9_HUMANBioGRID32296183 details
SRSF4_HUMANGEMI2_HUMANHPRD9447963 details
SRSF4_HUMANSCAFB_HUMANHPRD9447963 details
SRSF4_HUMAN1433G_HUMANIntAct17353931 details
SRSF4_HUMANSF3A2_HUMANBioGRID, MINT17332742 details
SRSF4_HUMANPRGC1_HUMANBioGRID, HPRD10983978 details
SRSF4_HUMANSRRM1_HUMANBioGRID16159877 9531537 details
SRSF4_HUMANNFX1_HUMANBioGRID17267499 details
SRSF4_HUMAN1433E_HUMANBioGRID19608861 details
SRSF4_HUMANU2AF2_HUMANBioGRID26641092 details
SRSF4_HUMANRBMX_HUMANBioGRID21723381 details
SRSF4_HUMANPCBP2_HUMANBioGRID21723381 details
SRSF4_HUMANSRPK1_HUMANHPRD10390541 8208298 details
SRSF4_HUMANSMUF1_HUMANHPRD15761153 details
SRSF4_HUMANSMUF2_HUMANHPRD15761153 details
SRSF4_HUMANFUS_HUMANHPRD12581738 details