Entity Details

Primary name KIF1A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ12756
EntryNameKIF1A_HUMAN
FullNameKinesin-like protein KIF1A
TaxID9606
Evidenceevidence at protein level
Length1690
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesKIF1A

GO terms

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GOName
GO:0003774 cytoskeletal motor activity
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0005871 kinesin complex
GO:0005874 microtubule
GO:0007018 microtubule-based movement
GO:0008017 microtubule binding
GO:0008021 synaptic vesicle
GO:0008089 anterograde axonal transport
GO:0008574 plus-end-directed microtubule motor activity
GO:0016192 vesicle-mediated transport
GO:0016887 ATP hydrolysis activity
GO:0022027 interkinetic nuclear migration
GO:0030424 axon
GO:0030425 dendrite
GO:0030705 cytoskeleton-dependent intracellular transport
GO:0042802 identical protein binding
GO:0043025 neuronal cell body
GO:0060998 regulation of dendritic spine development
GO:0061001 regulation of dendritic spine morphogenesis
GO:0098674 extrinsic component of neuronal dense core vesicle membrane
GO:0098794 postsynapse
GO:0098840 protein transport along microtubule
GO:0098992 neuronal dense core vesicle
GO:0099519 dense core granule cytoskeletal transport
GO:1904115 axon cytoplasm
GO:1990048 anterograde neuronal dense core vesicle transport
GO:1990049 retrograde neuronal dense core vesicle transport

Subcellular Location

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Subcellular Location
Cell junction
Cell projection
Cytoplasm
Cytoplasmic vesicle

Domains

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DomainNameCategoryType
IPR000253 Forkhead-associated (FHA) domainDomainDomain
IPR001752 Kinesin motor domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR008984 SMAD/FHA domain superfamilyFamilyHomologous superfamily
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR019821 Kinesin motor domain, conserved siteSiteConserved site
IPR022140 Kinesin-like KIF1-typeDomainDomain
IPR022164 Kinesin-likeDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR027640 Kinesin-like proteinFamilyFamily
IPR032405 Kinesin-associatedDomainDomain
IPR036961 Kinesin motor domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB03909 Adenosine-5'-[Beta, Gamma-Methylene]TriphosphateDrugbanksmall molecule
DB04395 Phosphoaminophosphonic Acid-Adenylate EsterDrugbanksmall molecule

Interactions

37 interactions

InteractorPartnerSourcesPublicationsLink
KIF1A_HUMANKIF1A_HUMANDIP, HPRD, MINT15014437 22863567 details
KIF1A_HUMANSP1_HUMANBioGRID, IntAct20195357 details
KIF1A_HUMANTRIP6_HUMANBioGRID, IntAct24722188 details
KIF1A_HUMANTRI27_HUMANBioGRID, IntAct24722188 details
KIF1A_HUMANTRAF1_HUMANBioGRID, IntAct24722188 details
KIF1A_HUMANTNS2_HUMANBioGRID, IntAct24722188 details
KIF1A_HUMANSPY2_HUMANBioGRID, IntAct24722188 details
KIF1A_HUMANRNF31_HUMANBioGRID, IntAct24722188 details
KIF1A_HUMANRGS20_HUMANBioGRID, IntAct24722188 details
KIF1A_HUMANRFX6_HUMANBioGRID, IntAct24722188 details
KIF1A_HUMANRBPMS_HUMANBioGRID, IntAct24722188 details
KIF1A_HUMANPSA3_HUMANBioGRID, IntAct24722188 details
KIF1A_HUMANPLS1_HUMANBioGRID, IntAct24722188 details
KIF1A_HUMANNT2NA_HUMANBioGRID, IntAct24722188 details
KIF1A_HUMANMTUS2_HUMANBioGRID, IntAct24722188 details
KIF1A_HUMANMKRN3_HUMANBioGRID, IntAct24722188 details
KIF1A_HUMANTRIM1_HUMANBioGRID, IntAct24722188 details
KIF1A_HUMANMDFI_HUMANBioGRID, IntAct24722188 details
KIF1A_HUMANFXR2_HUMANBioGRID, IntAct24722188 details
KIF1A_HUMANATL4_HUMANBioGRID, IntAct24722188 details
KIF1A_HUMANKIF1B_HUMANBioGRID, IntAct28514442 32814053 details
KIF1A_HUMANRETR1_HUMANDIP26040720 details
KIF1A_HUMANESR1_HUMANBioGRID, HPRD, IntAct15604093 31527615 details
KIF1A_HUMANCATD_HUMANIntAct32814053 details
KIF1A_HUMANGRN_HUMANIntAct32814053 details
KIF1A_HUMANTTHY_HUMANIntAct32814053 details
KIF1A_HUMANWFS1_HUMANIntAct32814053 details
KIF1A_HUMANSPRE1_HUMANIntAct32814053 details
KIF1A_HUMANMED1_HUMANBioGRID15604093 details
KIF1A_HUMANPPARG_HUMANBioGRID, HPRD15604093 details
KIF1A_HUMANRXRA_HUMANBioGRID, HPRD15604093 details
KIF1A_HUMANANDR_HUMANBioGRID, HPRD15604093 24722188 details
KIF1A_HUMANRIMB1_HUMANBioGRID24722188 details
KIF1A_HUMANNT2NC_HUMANBioGRID24722188 details
KIF1A_HUMANDISC1_HUMANIntAct31413325 details
KIF1A_HUMANTNIK_HUMANIntAct31413325 details
KIF1A_HUMANGIT1_HUMANHPRD12522103 details