Entity Details

Primary name ABCA7
Entity type gene
Source Source Link

Details

PrimaryID10347
RefseqGeneNG_046909
SymbolABCA7
NameATP binding cassette subfamily A member 7
Chromosome19
Location19p13.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-06-11
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsABCA7_HUMAN

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0001891 phagocytic cup
GO:0005319 lipid transporter activity
GO:0005524 ATP binding
GO:0005548 phospholipid transporter activity
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0006869 lipid transport
GO:0006909 phagocytosis
GO:0007613 memory
GO:0008542 visual learning
GO:0009986 cell surface
GO:0010875 positive regulation of cholesterol efflux
GO:0016021 integral component of membrane
GO:0018149 peptide cross-linking
GO:0019216 regulation of lipid metabolic process
GO:0030054 cell junction
GO:0031901 early endosome membrane
GO:0032587 ruffle membrane
GO:0033344 cholesterol efflux
GO:0033700 phospholipid efflux
GO:0034188 apolipoprotein A-I receptor activity
GO:0034205 amyloid-beta formation
GO:0034380 high-density lipoprotein particle assembly
GO:0034504 protein localization to nucleus
GO:0038027 apolipoprotein A-I-mediated signaling pathway
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0042985 negative regulation of amyloid precursor protein biosynthetic process
GO:0043231 intracellular membrane-bounded organelle
GO:0043409 negative regulation of MAPK cascade
GO:0044857 plasma membrane raft organization
GO:0045332 phospholipid translocation
GO:0045806 negative regulation of endocytosis
GO:0050766 positive regulation of phagocytosis
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0090554 phosphatidylcholine floppase activity
GO:0090556 phosphatidylserine floppase activity
GO:0097386 glial cell projection
GO:0140328 floppase activity
GO:0150094 amyloid-beta clearance by cellular catabolic process
GO:1900223 positive regulation of amyloid-beta clearance
GO:1901076 positive regulation of engulfment of apoptotic cell
GO:1902430 negative regulation of amyloid-beta formation
GO:1902991 regulation of amyloid precursor protein catabolic process
GO:1902995 positive regulation of phospholipid efflux
GO:1903898 negative regulation of PERK-mediated unfolded protein response
GO:2000010 positive regulation of protein localization to cell surface

Diseases

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Interactions

10 interactions

InteractorPartnerSourcesPublicationsLink
ABCA7ADRB2BioGRID, MINT28298427 details
ABCA7C5AR2BioGRID, MINT28298427 details
ABCA7LLGL2BioGRID, IntAct26496610 details
ABCA7SGTBBioGRID, IntAct26496610 details
ABCA7HNRNPDBioGRID, IntAct26496610 details
ABCA7SYNCRIPBioGRID, IntAct26496610 details
ABCA7SORT1BioGRID, IntAct26496610 details
ABCA7GABRA3BioGRID, IntAct28514442 details
ABCA7HTR3ABioGRID, IntAct28514442 details
ABCA7TAF1BioGRID31753913 details