Entity Details

Primary name HYAL2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ12891
EntryNameHYAL2_HUMAN
FullNameHyaluronidase-2
TaxID9606
Evidenceevidence at protein level
Length473
SequenceStatuscomplete
DateCreated2002-11-15
DateModified2021-06-02

Ontological Relatives

GenesHYAL2

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0000302 response to reactive oxygen species
GO:0001618 virus receptor activity
GO:0001822 kidney development
GO:0002244 hematopoietic progenitor cell differentiation
GO:0003713 transcription coactivator activity
GO:0004415 hyalurononglucosaminidase activity
GO:0005540 hyaluronic acid binding
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005902 microvillus
GO:0005975 carbohydrate metabolic process
GO:0006027 glycosaminoglycan catabolic process
GO:0009615 response to virus
GO:0009986 cell surface
GO:0010259 multicellular organism aging
GO:0010764 negative regulation of fibroblast migration
GO:0016324 apical plasma membrane
GO:0019064 fusion of virus membrane with host plasma membrane
GO:0019087 transformation of host cell by virus
GO:0019899 enzyme binding
GO:0030139 endocytic vesicle
GO:0030214 hyaluronan catabolic process
GO:0030294 receptor signaling protein tyrosine kinase inhibitor activity
GO:0030308 negative regulation of cell growth
GO:0030971 receptor tyrosine kinase binding
GO:0031362 anchored component of external side of plasma membrane
GO:0031410 cytoplasmic vesicle
GO:0032755 positive regulation of interleukin-6 production
GO:0032757 positive regulation of interleukin-8 production
GO:0033906 hyaluronoglucuronidase activity
GO:0035810 positive regulation of urine volume
GO:0042117 monocyte activation
GO:0042307 positive regulation of protein import into nucleus
GO:0043407 negative regulation of MAP kinase activity
GO:0044344 cellular response to fibroblast growth factor stimulus
GO:0045121 membrane raft
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046658 anchored component of plasma membrane
GO:0046677 response to antibiotic
GO:0046718 viral entry into host cell
GO:0048471 perinuclear region of cytoplasm
GO:0048705 skeletal system morphogenesis
GO:0050431 transforming growth factor beta binding
GO:0050729 positive regulation of inflammatory response
GO:0051216 cartilage development
GO:0051607 defense response to virus
GO:0051898 negative regulation of protein kinase B signaling
GO:0060586 multicellular organismal iron ion homeostasis
GO:0061099 negative regulation of protein tyrosine kinase activity
GO:0070295 renal water absorption
GO:0071347 cellular response to interleukin-1
GO:0071356 cellular response to tumor necrosis factor
GO:0071493 cellular response to UV-B
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:0090575 RNA polymerase II transcription regulator complex
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR013785 Aldolase-type TIM barrelFamilyHomologous superfamily
IPR017853 Glycoside hydrolase superfamilyFamilyHomologous superfamily
IPR018155 HyaluronidaseFamilyFamily

Diseases

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