Entity Details

Primary name LEFTY1
Entity type gene
Source Source Link

Details

PrimaryID10637
RefseqGene
SymbolLEFTY1
Nameleft-right determination factor 1
Chromosome1
Location1q42.12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-07-04
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsLFTY1_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0003007 heart morphogenesis
GO:0005125 cytokine activity
GO:0005160 transforming growth factor beta receptor binding
GO:0005615 extracellular space
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007368 determination of left/right symmetry
GO:0008083 growth factor activity
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0030509 BMP signaling pathway
GO:0060395 SMAD protein signal transduction

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
LEFTY1MTORBioGRID, IntAct28514442 details
LEFTY1LEFTY2BioGRID, IntAct28514442 details
LEFTY1SMAD3IntAct22036565 details
LEFTY1POU5F1IntAct22036565 details
LEFTY1WTAPBioGRID29489750 details