Entity Details

Primary name PLK2
Entity type gene
Source Source Link

Details

PrimaryID10769
RefseqGene
SymbolPLK2
Namepolo like kinase 2
Chromosome5
Location5q11.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-07-19
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsPLK2_HUMAN

GO terms

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GOName
GO:0000082 G1/S transition of mitotic cell cycle
GO:0000278 mitotic cell cycle
GO:0000785 chromatin
GO:0000922 spindle pole
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005814 centriole
GO:0005829 cytosol
GO:0006468 protein phosphorylation
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007052 mitotic spindle organization
GO:0007093 mitotic cell cycle checkpoint signaling
GO:0007265 Ras protein signal transduction
GO:0007613 memory
GO:0010508 positive regulation of autophagy
GO:0016525 negative regulation of angiogenesis
GO:0018105 peptidyl-serine phosphorylation
GO:0030425 dendrite
GO:0032092 positive regulation of protein binding
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032465 regulation of cytokinesis
GO:0032486 Rap protein signal transduction
GO:0043008 ATP-dependent protein binding
GO:0043066 negative regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0044877 protein-containing complex binding
GO:0045732 positive regulation of protein catabolic process
GO:0046599 regulation of centriole replication
GO:0048167 regulation of synaptic plasticity
GO:0060291 long-term synaptic potentiation
GO:0060292 long-term synaptic depression
GO:0061000 negative regulation of dendritic spine development
GO:0071866 negative regulation of apoptotic process in bone marrow cell
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:2000773 negative regulation of cellular senescence

Diseases

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Interactions

53 interactions

InteractorPartnerSourcesPublicationsLink
PLK2MPP3BioGRID, HPRD, IntAct16169070 details
PLK2CENPJMINT20531387 details
PLK2CASKBioGRID, IntAct21988832 details
PLK2CDC20BBioGRID, IntAct25416956 details
PLK2PLK1DIP19706541 details
PLK2CIB1BioGRID, HPRD10523297 12651910 details
PLK2NEDD4BioGRID19953087 details
PLK2SNCABioGRID19889641 22988096 details
PLK2APPBioGRID21832049 details
PLK2CENPUBioGRID19597481 details
PLK2TSC1BioGRID20054236 details
PLK2TSC2BioGRID20054236 details
PLK2ELP1IntAct16169070 details
PLK2DLGAP4IntAct16169070 details
PLK2FBXW7BioGRID27423313 details
PLK2CTSZBioGRID, IntAct26496610 details
PLK2C1orf226BioGRID, IntAct26496610 details
PLK2RTN4IP1BioGRID, IntAct26496610 details
PLK2LENG1BioGRID, IntAct26496610 details
PLK2IRGQBioGRID, IntAct26496610 details
PLK2ITPR1BioGRID, IntAct26496610 details
PLK2FGD6BioGRID, IntAct26496610 details
PLK2PCGF5BioGRID, IntAct26496610 details
PLK2MYO18ABioGRID, IntAct26496610 details
PLK2DNTTIP1BioGRID, IntAct26496610 details
PLK2MFN1BioGRID, IntAct26496610 details
PLK2THRAP3BioGRID, IntAct26496610 details
PLK2CPA4BioGRID, IntAct26186194 28514442 details
PLK2RNASE7BioGRID, IntAct26186194 28514442 details
PLK2POF1BBioGRID, IntAct26186194 28514442 details
PLK2SDR9C7BioGRID, IntAct26186194 28514442 details
PLK2ANKRD44BioGRID, IntAct26186194 28514442 details
PLK2SUGP1BioGRID, IntAct26186194 28514442 details
PLK2SERPINA12BioGRID, IntAct26186194 28514442 details
PLK2TAF8BioGRID, IntAct26186194 28514442 details
PLK2RABL6BioGRID, IntAct26186194 28514442 details
PLK2PAK2BioGRID, IntAct26186194 28514442 details
PLK2ALADBioGRID, IntAct28514442 details
PLK2SERPINA1BioGRID, IntAct26186194 28514442 details
PLK2SERPINB7BioGRID, IntAct26186194 28514442 details
PLK2CTSVBioGRID, IntAct26186194 28514442 details
PLK2ANKRD28BioGRID, IntAct26186194 28514442 details
PLK2KLK7BioGRID26186194 details
PLK2EIF5BBioGRID26186194 details
PLK2CCDC12BioGRID26186194 details
PLK2EEF1A2BioGRID26186194 details
PLK2SAR1BBioGRID26186194 details
PLK2CSTF1BioGRID26186194 details
PLK2XPO1BioGRID26673895 details
PLK2FXR1BioGRID26496610 details
PLK2RNF4BioGRID29180619 details
PLK2UNKBioGRID25737280 details
PLK2VIRMABioGRID29507755 details