Entity Details

Primary name CLN3
Entity type gene
Source Source Link

Details

PrimaryID1201
RefseqGeneNG_008654
SymbolCLN3
NameCLN3 lysosomal/endosomal transmembrane protein, battenin
Chromosome16
Location16p12.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1990-06-13
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCLN3_HUMAN

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0001508 action potential
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005769 early endosome
GO:0005770 late endosome
GO:0005773 vacuole
GO:0005776 autophagosome
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005795 Golgi stack
GO:0005802 trans-Golgi network
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005901 caveola
GO:0006898 receptor-mediated endocytosis
GO:0007040 lysosome organization
GO:0007042 lysosomal lumen acidification
GO:0007611 learning or memory
GO:0008021 synaptic vesicle
GO:0008306 associative learning
GO:0009992 cellular water homeostasis
GO:0010762 regulation of fibroblast migration
GO:0015809 arginine transport
GO:0016021 integral component of membrane
GO:0016485 protein processing
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0031901 early endosome membrane
GO:0031902 late endosome membrane
GO:0032228 regulation of synaptic transmission, GABAergic
GO:0035235 ionotropic glutamate receptor signaling pathway
GO:0035752 lysosomal lumen pH elevation
GO:0036359 renal potassium excretion
GO:0042133 neurotransmitter metabolic process
GO:0042987 amyloid precursor protein catabolic process
GO:0042998 positive regulation of Golgi to plasma membrane protein transport
GO:0043005 neuron projection
GO:0043066 negative regulation of apoptotic process
GO:0043086 negative regulation of catalytic activity
GO:0043524 negative regulation of neuron apoptotic process
GO:0044754 autolysosome
GO:0044857 plasma membrane raft organization
GO:0045121 membrane raft
GO:0045861 negative regulation of proteolysis
GO:0046474 glycerophospholipid biosynthetic process
GO:0046836 glycolipid transport
GO:0047496 vesicle transport along microtubule
GO:0048172 regulation of short-term neuronal synaptic plasticity
GO:0048549 positive regulation of pinocytosis
GO:0050885 neuromuscular process controlling balance
GO:0051453 regulation of intracellular pH
GO:0051480 regulation of cytosolic calcium ion concentration
GO:0051493 regulation of cytoskeleton organization
GO:0051861 glycolipid binding
GO:0051966 regulation of synaptic transmission, glutamatergic
GO:0055037 recycling endosome
GO:0061024 membrane organization
GO:0061909 autophagosome-lysosome fusion
GO:0070613 regulation of protein processing
GO:0090160 Golgi to lysosome transport
GO:0090384 phagosome-lysosome docking
GO:0090385 phagosome-lysosome fusion
GO:0097352 autophagosome maturation
GO:0106049 regulation of cellular response to osmotic stress
GO:0120146 sulfatide binding
GO:1900079 regulation of arginine biosynthetic process
GO:1901096 regulation of autophagosome maturation
GO:1903076 regulation of protein localization to plasma membrane
GO:1905146 lysosomal protein catabolic process
GO:1905162 regulation of phagosome maturation
GO:1905244 regulation of modification of synaptic structure
GO:2001288 positive regulation of caveolin-mediated endocytosis

Diseases

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Interactions

96 interactions

InteractorPartnerSourcesPublicationsLink
CLN3CDHR3IntAct32814053 details
CLN3MAGEB6IntAct32814053 details
CLN3IFT20IntAct32814053 details
CLN3SBDSBioGRID20015955 details
CLN3KCNIP3BioGRID17189291 details
CLN3CLN5IntAct12134079 details
CLN3SEC61A2BioGRID, IntAct20562859 details
CLN3IRAK1BioGRID, IntAct20562859 details
CLN3XPOTBioGRID, IntAct20562859 details
CLN3DDX20BioGRID, IntAct20562859 details
CLN3CCDC47BioGRID, IntAct20562859 details
CLN3SIGMAR1BioGRID, IntAct20562859 details
CLN3UNC45ABioGRID, IntAct20562859 details
CLN3AFG3L2BioGRID, IntAct20562859 details
CLN3ESYT2BioGRID, IntAct20562859 details
CLN3NPEPPSBioGRID, IntAct20562859 details
CLN3RPN2BioGRID, IntAct20562859 23464991 details
CLN3GEMIN4BioGRID, IntAct20562859 details
CLN3GANABBioGRID, IntAct20562859 details
CLN3TRIP13BioGRID, IntAct20562859 details
CLN3XPO1BioGRID, IntAct20562859 23464991 details
CLN3HSD17B12BioGRID, IntAct20562859 23464991 details
CLN3FANCIBioGRID, IntAct20562859 details
CLN3PHBBioGRID, IntAct20562859 details
CLN3ABCD3BioGRID, IntAct20562859 details
CLN3CYC1BioGRID, IntAct20562859 details
CLN3VDAC2BioGRID, IntAct20562859 details
CLN3SLC25A10BioGRID, IntAct20562859 23464991 details
CLN3IMMTBioGRID, IntAct20562859 23464991 details
CLN3NUP93BioGRID, IntAct20562859 details
CLN3AUP1BioGRID, IntAct20562859 23464991 details
CLN3NUP205BioGRID, IntAct20562859 23464991 details
CLN3ATG7BioGRID, IntAct20562859 details
CLN3RIF1BioGRID, IntAct20562859 details
CLN3SLC25A11BioGRID, IntAct20562859 23464991 details
CLN3PRKDCBioGRID, IntAct20562859 23464991 details
CLN3COX15BioGRID, IntAct20562859 23464991 details
CLN3SLC25A22BioGRID, IntAct20562859 23464991 details
CLN3CLN3IntAct20562859 details
CLN3GCN1BioGRID, IntAct20562859 23464991 details
CLN3TELO2BioGRID, IntAct20562859 details
CLN3SFXN4BioGRID, IntAct20562859 details
CLN3CKAP4BioGRID20562859 details
CLN3DDOSTBioGRID20562859 23464991 details
CLN3CAND1BioGRID20562859 details
CLN3CPT1ABioGRID20562859 23464991 details
CLN3ILVBLBioGRID20562859 details
CLN3TMPOBioGRID20562859 details
CLN3SLC25A4BioGRID23464991 details
CLN3SLC25A5BioGRID23464991 details
CLN3SLC25A6BioGRID23464991 details
CLN3SLC25A13BioGRID23464991 details
CLN3ATP2A2BioGRID23464991 details
CLN3PHGDHBioGRID23464991 details
CLN3SFXN3BioGRID23464991 details
CLN3SLC25A3BioGRID23464991 details
CLN3ARF4BioGRID23464991 details
CLN3TECRBioGRID23464991 details
CLN3DBHBioGRID23464991 details
CLN3SFXN1BioGRID23464991 details
CLN3TMEM33BioGRID23464991 details
CLN3HACD3BioGRID23464991 details
CLN3ADGRL2BioGRID23464991 details
CLN3DPM1BioGRID23464991 details
CLN3SLC25A1BioGRID23464991 details
CLN3SSR4BioGRID23464991 details
CLN3RPN1BioGRID23464991 details
CLN3XPO5BioGRID23464991 details
CLN3RCN2BioGRID23464991 details
CLN3CALUBioGRID23464991 details
CLN3FADS2BioGRID23464991 details
CLN3UQCRC2BioGRID23464991 details
CLN3SCAMP3BioGRID23464991 details
CLN3ERLIN2BioGRID23464991 details
CLN3ARF3BioGRID23464991 details
CLN3ATP1A1BioGRID23464991 details
CLN3ARF5BioGRID23464991 details
CLN3FKBP8BioGRID23464991 details
CLN3MICOS13BioGRID23464991 details
CLN3SAMM50BioGRID23464991 details
CLN3CDS2BioGRID23464991 details
CLN3STRA6BioGRID23464991 details
CLN3SEC61A1BioGRID23464991 details
CLN3EMDBioGRID23464991 details
CLN3ATP5MGBioGRID23464991 details
CLN3FAR1BioGRID23464991 details
CLN3ARMC6BioGRID23464991 details
CLN3LPGAT1BioGRID23464991 details
CLN3SLC35B2BioGRID23464991 details
CLN3TFRCBioGRID23464991 details
CLN3CSE1LBioGRID23464991 details
CLN3PTH1RBioGRID26186194 details
CLN3RARS2BioGRID26186194 details
CLN3B3GALT2BioGRID26186194 details
CLN3NPC1BioGRID33144569 details
CLN3ELAVL1BioGRID19322201 details