Entity Details

Primary name CRFR2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13324
EntryNameCRFR2_HUMAN
FullNameCorticotropin-releasing factor receptor 2
TaxID9606
Evidenceevidence at protein level
Length411
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesCRHR2

GO terms

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GOName
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO:0008528 G protein-coupled peptide receptor activity
GO:0015056 corticotrophin-releasing factor receptor activity
GO:0017046 peptide hormone binding
GO:0030425 dendrite
GO:0043404 corticotropin-releasing hormone receptor activity
GO:0043679 axon terminus
GO:0060291 long-term synaptic potentiation

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000832 GPCR, family 2, secretin-likeFamilyFamily
IPR001879 GPCR, family 2, extracellular hormone receptor domainDomainDomain
IPR003051 GPCR, family 2, corticotropin releasing factor receptorFamilyFamily
IPR003053 GPCR, family 2, corticotropin releasing factor receptor, type 2FamilyFamily
IPR017981 GPCR, family 2-likeDomainDomain
IPR017983 GPCR, family 2, secretin-like, conserved siteSiteConserved site
IPR036445 GPCR family 2, extracellular hormone receptor domain superfamilyFamilyHomologous superfamily

Diseases

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