Entity Details

Primary name KCC1A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14012
EntryNameKCC1A_HUMAN
FullNameCalcium/calmodulin-dependent protein kinase type 1
TaxID9606
Evidenceevidence at protein level
Length370
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesCAMK1

GO terms

Show/Hide Table
GOName
GO:0004683 calmodulin-dependent protein kinase activity
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005829 cytosol
GO:0006468 protein phosphorylation
GO:0006913 nucleocytoplasmic transport
GO:0007049 cell cycle
GO:0007165 signal transduction
GO:0007268 chemical synaptic transmission
GO:0007399 nervous system development
GO:0010976 positive regulation of neuron projection development
GO:0014069 postsynaptic density
GO:0018105 peptidyl-serine phosphorylation
GO:0030154 cell differentiation
GO:0032091 negative regulation of protein binding
GO:0032880 regulation of protein localization
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0043393 regulation of protein binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046827 positive regulation of protein export from nucleus
GO:0051147 regulation of muscle cell differentiation
GO:0051149 positive regulation of muscle cell differentiation
GO:0051835 positive regulation of synapse structural plasticity
GO:0060143 positive regulation of syncytium formation by plasma membrane fusion
GO:0060999 positive regulation of dendritic spine development
GO:0071902 positive regulation of protein serine/threonine kinase activity
GO:0098978 glutamatergic synapse
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1901985 positive regulation of protein acetylation

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB12010 FostamatinibDrugbanksmall molecule

Interactions

29 interactions

InteractorPartnerSourcesPublicationsLink
KCC1A_HUMANHSPB1_HUMANBioGRID, IntAct25277244 details
KCC1A_HUMANP55G_HUMANBioGRID, IntAct25814554 details
KCC1A_HUMANATX1_HUMANBioGRID, IntAct32296183 32814053 details
KCC1A_HUMANIL16_HUMANBioGRID, IntAct28514442 32296183 details
KCC1A_HUMANCALM2_HUMANDIP, HPRD12475216 20668654 7559563 details
KCC1A_HUMANHD_HUMANIntAct32814053 details
KCC1A_HUMANKKCC2_HUMANBioGRID, HPRD10187789 11395482 9822657 details
KCC1A_HUMANGCM1_HUMANBioGRID21791615 details
KCC1A_HUMANA4_HUMANBioGRID21832049 details
KCC1A_HUMANCDN1B_HUMANBioGRID23707388 details
KCC1A_HUMANCCND1_HUMANBioGRID23707388 details
KCC1A_HUMANCDK4_HUMANBioGRID23707388 details
KCC1A_HUMANMARK2_HUMANBioGRID17442826 details
KCC1A_HUMANPP2AA_HUMANBioGRID24841198 details
KCC1A_HUMANPPME1_HUMANBioGRID24841198 details
KCC1A_HUMANFBX7_HUMANBioGRID27503909 details
KCC1A_HUMANPTN6_HUMANDIP25915125 details
KCC1A_HUMANHDAC4_HUMANBioGRID16767219 details
KCC1A_HUMANHDAC5_HUMANBioGRID, HPRD11081517 11114197 15367659 16767219 details
KCC1A_HUMANHDAC9_HUMANBioGRID15166223 details
KCC1A_HUMANSYN1_HUMANHPRD10571231 12237306 9395448 details
KCC1A_HUMANCALM1_HUMANHPRD12475216 7559563 details
KCC1A_HUMANCALM3_HUMANHPRD12475216 7559563 details
KCC1A_HUMANKCC1A_HUMANHPRD7641687 details
KCC1A_HUMANIF4G3_HUMANHPRD14507913 details
KCC1A_HUMANKKCC1_HUMANHPRD10187789 9705275 details
KCC1A_HUMANATF1_HUMANHPRD8384217 details
KCC1A_HUMANG3P_HUMANHPRD15680915 details
KCC1A_HUMANNOS1_HUMANHPRD10400690 10874031 12630910 1375933 15251453 details