Entity Details

Primary name NCSTN
Entity type gene
Source Source Link

Details

PrimaryID23385
RefseqGeneNG_027935
SymbolNCSTN
Namenicastrin
Chromosome1
Location1q23.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-05-01
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsNICA_HUMAN

GO terms

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GOName
GO:0002262 myeloid cell homeostasis
GO:0004175 endopeptidase activity
GO:0005739 mitochondrion
GO:0005765 lysosomal membrane
GO:0005769 early endosome
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005925 focal adhesion
GO:0006508 proteolysis
GO:0006509 membrane protein ectodomain proteolysis
GO:0007212 dopamine receptor signaling pathway
GO:0007215 glutamate receptor signaling pathway
GO:0007220 Notch receptor processing
GO:0007611 learning or memory
GO:0008021 synaptic vesicle
GO:0010008 endosome membrane
GO:0010950 positive regulation of endopeptidase activity
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016485 protein processing
GO:0021549 cerebellum development
GO:0022010 central nervous system myelination
GO:0030534 adult behavior
GO:0030674 protein-macromolecule adaptor activity
GO:0031293 membrane protein intracellular domain proteolysis
GO:0034205 amyloid-beta formation
GO:0035333 Notch receptor processing, ligand-dependent
GO:0035577 azurophil granule membrane
GO:0042098 T cell proliferation
GO:0042383 sarcolemma
GO:0042470 melanosome
GO:0042982 amyloid precursor protein metabolic process
GO:0042983 amyloid precursor protein biosynthetic process
GO:0042986 positive regulation of amyloid precursor protein biosynthetic process
GO:0042987 amyloid precursor protein catabolic process
GO:0043065 positive regulation of apoptotic process
GO:0043085 positive regulation of catalytic activity
GO:0043312 neutrophil degranulation
GO:0048013 ephrin receptor signaling pathway
GO:0050673 epithelial cell proliferation
GO:0051117 ATPase binding
GO:0051402 neuron apoptotic process
GO:0070062 extracellular exosome
GO:0070765 gamma-secretase complex
GO:0070851 growth factor receptor binding
GO:0071277 cellular response to calcium ion
GO:0099056 integral component of presynaptic membrane
GO:1900271 regulation of long-term synaptic potentiation
GO:1990000 amyloid fibril formation
GO:1990926 short-term synaptic potentiation

Diseases

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Interactions

167 interactions

InteractorPartnerSourcesPublicationsLink
NCSTNPSEN1BioGRID, HPRD, IntAct, MINT, UniProt10993067 12297508 12471034 12603837 14572442 15257293 15474363 16641999 17911105 18201567 18667537 28351972 29611543 30559186 details
NCSTNBSGBioGRID, IntAct, UniProt15890777 26496610 details
NCSTNBACE1BioGRID, HPRD12054507 details
NCSTNSPP1BioGRID22779921 details
NCSTNMAPK9BioGRID18667537 details
NCSTNABL1HPRD12021275 details
NCSTNTMED10HPRD, IntAct16641999 details
NCSTNPSENENBioGRID, HPRD, IntAct, MINT, UniProt12198112 14572442 15322109 16641999 18201567 18667537 22074918 details
NCSTNTGOLN2MINT18201567 details
NCSTNGOLGA2MINT18201567 details
NCSTNLAMP1MINT18201567 details
NCSTNAPH1ABioGRID, DIP, HPRD, IntAct, MINT12297508 12471034 12857757 14572442 15257293 15474363 17911105 18201567 18667537 19376115 26280335 details
NCSTNERLIN2BioGRID, IntAct22771797 26496610 details
NCSTNPSEN2BioGRID, HPRD10993067 12297508 15474363 details
NCSTNAPPBioGRID, HPRD10993067 details
NCSTNATP6V1B1BioGRID21674799 details
NCSTNAPH1BBioGRID, HPRD12297508 12857757 15474363 details
NCSTNGSAPBioGRID20811458 details
NCSTNLGALS3BioGRID24755837 details
NCSTNMAD2L2BioGRID30022168 details
NCSTNTMED2IntAct16641999 details
NCSTNATP6V1AIntAct21674799 details
NCSTNNDUFA9IntAct20515039 details
NCSTNTRMT6BioGRID, IntAct26496610 details
NCSTNSLC7A5BioGRID, IntAct26496610 details
NCSTNTCTN3BioGRID, IntAct26496610 details
NCSTNSLC25A12BioGRID, IntAct26496610 details
NCSTNSPTLC1BioGRID, IntAct26496610 details
NCSTNYIF1ABioGRID, IntAct26496610 details
NCSTNMAGT1BioGRID, IntAct26496610 details
NCSTNTRIP13BioGRID, IntAct26496610 details
NCSTNTTI1BioGRID, IntAct26496610 details
NCSTNNDUFB5BioGRID, IntAct26496610 details
NCSTNELL2BioGRID, IntAct26496610 details
NCSTNFAM111ABioGRID, IntAct26496610 details
NCSTNSRPRBBioGRID, IntAct26496610 details
NCSTNWLSBioGRID, IntAct26496610 details
NCSTNSQORBioGRID, IntAct26496610 details
NCSTNMAGED2BioGRID, IntAct26496610 details
NCSTNPNKDBioGRID, IntAct26496610 details
NCSTNRPP38BioGRID, IntAct26496610 details
NCSTNFASTKD5BioGRID, IntAct26496610 details
NCSTNALDOABioGRID, IntAct26496610 details
NCSTNSLC2A1BioGRID, IntAct26496610 details
NCSTNATP2A2BioGRID, IntAct26496610 details
NCSTNSCAMP3BioGRID, IntAct26496610 details
NCSTNPRSS21BioGRID, IntAct26496610 details
NCSTNSFXN1BioGRID, IntAct26496610 details
NCSTNIMMTBioGRID, IntAct26496610 details
NCSTNTIMM29BioGRID, IntAct26496610 details
NCSTNTOMM20BioGRID, IntAct26496610 details
NCSTNCRNKL1BioGRID, IntAct26496610 details
NCSTNMMS19BioGRID, IntAct26496610 details
NCSTNATP5F1ABioGRID, IntAct26496610 details
NCSTNEBPBioGRID, IntAct26496610 details
NCSTNATP1A1BioGRID, IntAct26496610 details
NCSTNCLPTM1LBioGRID, IntAct26496610 details
NCSTNSLC25A5BioGRID, IntAct26496610 details
NCSTNRRASBioGRID, IntAct28514442 details
NCSTNMICAL1BioGRID, IntAct28514442 details
NCSTNNCAM1BioGRID, IntAct28514442 details
NCSTNPAG1BioGRID, IntAct28514442 details
NCSTNAHNAK2BioGRID, IntAct28514442 details
NCSTNEEPD1BioGRID, IntAct28514442 details
NCSTNVASNBioGRID, DIP, IntAct18942891 28514442 details
NCSTNEEF1A2BioGRID, IntAct28514442 details
NCSTNACTA1BioGRID, IntAct28514442 details
NCSTNEPHA2BioGRID, IntAct28514442 details
NCSTNPTPRGBioGRID, IntAct28514442 details
NCSTNSRCBioGRID, IntAct28514442 details
NCSTNRAP2ABioGRID, IntAct28514442 details
NCSTNALOX5BioGRID, IntAct28514442 details
NCSTNYES1BioGRID, IntAct28514442 details
NCSTNDNERDIP18942891 details
NCSTNNPR1DIP18942891 details
NCSTNPLXDC2DIP18942891 details
NCSTNDSG2DIP18942891 details
NCSTNDAG1DIP18942891 details
NCSTNCANXBioGRID, IntAct29568061 details
NCSTNFLOT2UniProt25893612 details
NCSTNSTXBP1UniProt25893612 details
NCSTNGAP43UniProt25893612 details
NCSTNSLC2A3UniProt25893612 details
NCSTNADAM10UniProt30538620 details
NCSTNCD81IntAct32900848 details
NCSTNFBXO6BioGRID22268729 32409323 details
NCSTNRPS14BioGRID22939629 details
NCSTNTHRAP3BioGRID22939629 details
NCSTNRAD50BioGRID22939629 details
NCSTNSRSF11BioGRID22939629 details
NCSTNSEPTIN7BioGRID22939629 details
NCSTNSEPTIN2BioGRID22939629 details
NCSTNFTSJ3BioGRID22939629 details
NCSTNUSP39BioGRID22939629 details
NCSTNUTP14ABioGRID22939629 details
NCSTNRPS11BioGRID22939629 details
NCSTNRBM25BioGRID22939629 details
NCSTNPRPF6BioGRID22939629 details
NCSTNSRSF10BioGRID22939629 details
NCSTNRRS1BioGRID22939629 details
NCSTNTRA2ABioGRID22939629 details
NCSTNTRIM55BioGRID22939629 details
NCSTNRRP7ABioGRID22939629 details
NCSTNPSIP1BioGRID22939629 details
NCSTNNUMA1BioGRID22939629 details
NCSTNNOP56BioGRID22939629 details
NCSTNTOP1BioGRID22939629 details
NCSTNPHGDHBioGRID22939629 details
NCSTNSURF4BioGRID22939629 details
NCSTNRCC1BioGRID22939629 details
NCSTNTOP2BBioGRID22939629 details
NCSTNPRPF40ABioGRID22939629 details
NCSTNSMARCC2BioGRID22939629 details
NCSTNSRSF1BioGRID22939629 details
NCSTNRFC4BioGRID22939629 details
NCSTNSAP18BioGRID22939629 details
NCSTNNOP58BioGRID22939629 details
NCSTNSUPT16HBioGRID22939629 details
NCSTNU2AF1BioGRID22939629 details
NCSTNNOP16BioGRID22939629 details
NCSTNSLC27A2BioGRID22939629 details
NCSTNRCC2BioGRID22939629 details
NCSTNBCAS2BioGRID22939629 details
NCSTNNOP2BioGRID22939629 details
NCSTNPCDHA2BioGRID22939629 details
NCSTNTPBGBioGRID22939629 details
NCSTNGTF3C1BioGRID22939629 details
NCSTNS100A9BioGRID22939629 details
NCSTNSNRPD2BioGRID22939629 details
NCSTNSSRP1BioGRID22939629 details
NCSTNRPS7BioGRID22939629 details
NCSTNIKBioGRID22939629 details
NCSTNDPF2BioGRID22939629 details
NCSTNSMARCA5BioGRID22939629 details
NCSTNSMARCB1BioGRID22939629 details
NCSTNLMNB1BioGRID22939629 details
NCSTNLAMP2BioGRID22939629 details
NCSTNSART1BioGRID22939629 details
NCSTNTRMT112BioGRID22939629 details
NCSTNWDR18BioGRID22939629 details
NCSTNRSL1D1BioGRID22939629 details
NCSTNSMU1BioGRID22939629 details
NCSTNZC3H18BioGRID22939629 details
NCSTNHNRNPUBioGRID22939629 details
NCSTNRAB31BioGRID22939629 details
NCSTNMYBBP1ABioGRID22939629 details
NCSTNSAFBBioGRID22939629 details
NCSTNTMEM14BBioGRID22939629 details
NCSTNHNRNPRBioGRID22939629 details
NCSTNHNRNPFBioGRID26344197 details
NCSTNKHDRBS1BioGRID26344197 details
NCSTNNTRK1BioGRID25921289 details
NCSTNEWSR1BioGRID24999758 details
NCSTNESYT2BioGRID26496610 details
NCSTNRNF4BioGRID29180619 details
NCSTNMEPCEBioGRID29845934 details
NCSTNPTPROBioGRID28675297 details
NCSTNLMBR1LBioGRID31073040 details
NCSTNRETBioGRID32062451 details
NCSTNNPC1BioGRID33144569 details
NCSTNLGALS9BioGRID31995728 details
NCSTNMARCHF3BioGRID32614325 details
NCSTNMARCHF4BioGRID32614325 details
NCSTNLRRC59BioGRID34079125 details
NCSTNSYNE3BioGRID34079125 details
NCSTNELAVL1BioGRID19322201 details
NCSTNDDX58BioGRID32513696 details