Entity Details

Primary name STAP1
Entity type gene
Source Source Link

Details

PrimaryID26228
RefseqGeneNG_047142
SymbolSTAP1
Namesignal transducing adaptor family member 1
Chromosome4
Location4q13.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-02-20
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSTAP1_HUMAN

GO terms

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GOName
GO:0001784 phosphotyrosine residue binding
GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005157 macrophage colony-stimulating factor receptor binding
GO:0005543 phospholipid binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0010628 positive regulation of gene expression
GO:0010760 negative regulation of macrophage chemotaxis
GO:0019901 protein kinase binding
GO:0032991 protein-containing complex
GO:0035591 signaling adaptor activity
GO:0042326 negative regulation of phosphorylation
GO:0043231 intracellular membrane-bounded organelle
GO:0050861 positive regulation of B cell receptor signaling pathway
GO:0060100 positive regulation of phagocytosis, engulfment
GO:0071222 cellular response to lipopolysaccharide
GO:1900028 negative regulation of ruffle assembly
GO:1902227 negative regulation of macrophage colony-stimulating factor signaling pathway
GO:1903980 positive regulation of microglial cell activation
GO:1903997 positive regulation of non-membrane spanning protein tyrosine kinase activity
GO:1904140 negative regulation of microglial cell migration
GO:1904151 positive regulation of microglial cell mediated cytotoxicity
GO:2000251 positive regulation of actin cytoskeleton reorganization

Diseases

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