Entity Details

Primary name NSMCE2
Entity type gene
Source Source Link

Details

PrimaryID286053
RefseqGeneNG_053069
SymbolNSMCE2
NameNSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase
Chromosome8
Location8q24.13
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2002-12-14
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsNSE2_HUMAN

GO terms

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GOName
GO:0000722 telomere maintenance via recombination
GO:0000724 double-strand break repair via homologous recombination
GO:0000781 chromosome, telomeric region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0007049 cell cycle
GO:0008270 zinc ion binding
GO:0016604 nuclear body
GO:0016605 PML body
GO:0016925 protein sumoylation
GO:0019789 SUMO transferase activity
GO:0030915 Smc5-Smc6 complex
GO:0034184 positive regulation of maintenance of mitotic sister chromatid cohesion
GO:0045842 positive regulation of mitotic metaphase/anaphase transition
GO:0051301 cell division
GO:0061665 SUMO ligase activity
GO:0090398 cellular senescence

Diseases

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Interactions

35 interactions

InteractorPartnerSourcesPublicationsLink
NSMCE2TXLNABioGRID, IntAct25416956 32296183 details
NSMCE2ELAVL4IntAct32814053 details
NSMCE2FGFR3IntAct32814053 details
NSMCE2GSNIntAct32814053 details
NSMCE2KIF1BIntAct32814053 details
NSMCE2SPRED1IntAct32814053 details
NSMCE2RAD21BioGRID22751501 details
NSMCE2SMC5BioGRID16055714 22751501 26344197 32389690 details
NSMCE2ETV1BioGRID16055714 details
NSMCE2TSNAXBioGRID16055714 details
NSMCE2USP28BioGRID25359778 details
NSMCE2SMC6BioGRID, IntAct, UniProt18086888 22751501 26344197 26496610 details
NSMCE2NSMCE1BioGRID, IntAct, UniProt18086888 26186194 26344197 28514442 32389690 details
NSMCE2EID3BioGRID, IntAct26186194 28514442 32389690 details
NSMCE2STAG2BioGRID22751501 details
NSMCE2SMC1ABioGRID22751501 details
NSMCE2SMC3BioGRID22751501 details
NSMCE2PDS5ABioGRID22751501 details
NSMCE2PDS5BBioGRID22751501 details
NSMCE2WAPLBioGRID22751501 details
NSMCE2TM9SF4BioGRID, IntAct26496610 details
NSMCE2NIPSNAP1BioGRID, IntAct26496610 details
NSMCE2ILKBioGRID, IntAct26496610 details
NSMCE2SYNCRIPBioGRID, IntAct26496610 details
NSMCE2SORT1BioGRID, IntAct26496610 details
NSMCE2SAMD1BioGRID, IntAct26496610 details
NSMCE2ZNF597BioGRID, IntAct26186194 28514442 details
NSMCE2BRCA1BioGRID, UniProt29656893 details
NSMCE2ENGBioGRID, UniProt31540324 details
NSMCE2PAN2BioGRID23398456 details
NSMCE2NSMCE3BioGRID26344197 details
NSMCE2EWSR1BioGRID24999758 details
NSMCE2RNF4BioGRID29180619 details
NSMCE2BCAR1BioGRID33001583 details
NSMCE2HNRNPLBioGRID28611215 details