Entity Details

Primary name IRF7
Entity type gene
Source Source Link

Details

PrimaryID3665
RefseqGeneNG_029106
SymbolIRF7
Nameinterferon regulatory factor 7
Chromosome11
Location11p15.5
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1997-10-16
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsIRF7_HUMAN

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0002376 immune system process
GO:0002819 regulation of adaptive immune response
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006974 cellular response to DNA damage stimulus
GO:0009615 response to virus
GO:0010008 endosome membrane
GO:0016064 immunoglobulin mediated immune response
GO:0019043 establishment of viral latency
GO:0032479 regulation of type I interferon production
GO:0032481 positive regulation of type I interferon production
GO:0032727 positive regulation of interferon-alpha production
GO:0032728 positive regulation of interferon-beta production
GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway
GO:0034127 regulation of MyD88-independent toll-like receptor signaling pathway
GO:0035666 TRIF-dependent toll-like receptor signaling pathway
GO:0039530 MDA-5 signaling pathway
GO:0045087 innate immune response
GO:0045655 regulation of monocyte differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0050776 regulation of immune response
GO:0051607 defense response to virus
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0060337 type I interferon signaling pathway
GO:0060340 positive regulation of type I interferon-mediated signaling pathway
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000110 negative regulation of macrophage apoptotic process

Diseases

Show/Hide Table

Interactions

80 interactions

InteractorPartnerSourcesPublicationsLink
IRF7TBK1BioGRID, MINT17599067 details
IRF7UBE2BIntAct19549727 details
IRF7ACADSBioGRID, IntAct21988832 details
IRF7GCLMBioGRID, IntAct21988832 details
IRF7INSRBioGRID, IntAct21988832 details
IRF7TRAF6BioGRID, HPRD, InnateDB15361868 18710948 21183682 21743479 22095711 26224488 30927622 details
IRF7IRAK1BioGRID, HPRD, IntAct15767370 21903422 details
IRF7PALD1BioGRID, IntAct21903422 details
IRF7CCDC47BioGRID, IntAct21903422 details
IRF7ARAFBioGRID, IntAct21903422 details
IRF7AIPBioGRID, IntAct21903422 details
IRF7TLK2BioGRID, IntAct21903422 details
IRF7LTN1BioGRID, IntAct21903422 details
IRF7TRMT61BBioGRID, IntAct21903422 30833792 details
IRF7CHUKUniProt18922877 details
IRF7TP53BioGRID, IntAct18307271 25505178 details
IRF7IRF3BioGRID, HPRD11162841 18641315 details
IRF7IRF7BioGRID11162841 22588174 details
IRF7TANKBioGRID17823124 details
IRF7MYD88BioGRID, HPRD15361868 16484229 details
IRF7EP300BioGRID, HPRD12604599 details
IRF7CREBBPBioGRID, HPRD12604599 details
IRF7TRIM28BioGRID21940674 details
IRF7SMAD3BioGRID14729983 details
IRF7SMAD4BioGRID14729983 details
IRF7SMAD2BioGRID14729983 details
IRF7SOCS1BioGRID29712772 details
IRF7SOCS3BioGRID29712772 details
IRF7TICAM1HPRD14739303 details
IRF7PIAS4BioGRID, HPRD, MINT15251447 details
IRF7MAFBBioGRID, InnateDB20581830 details
IRF7IKBKEUniProt19153231 details
IRF7ALKBioGRID14968112 details
IRF7FADDBioGRID21183682 details
IRF7TNFAIP3BioGRID20392859 details
IRF7TRIM21BioGRID20668674 details
IRF7MAVSBioGRID, HPRD16153868 details
IRF7DEAF1BioGRID23846693 details
IRF7NMIBioGRID23956435 details
IRF7SUMO2BioGRID24267727 details
IRF7SUMO3BioGRID24267727 details
IRF7RNF31BioGRID27903798 details
IRF7OTUD1BioGRID30100102 details
IRF7TARBP2BioGRID30927622 details
IRF7KAT2AHPRD12374802 details
IRF7KAT2BHPRD12374802 details
IRF7TICAM2HPRD14517278 details
IRF7IQSEC1BioGRID, IntAct21903422 details
IRF7P4HA1BioGRID, IntAct21903422 details
IRF7HACE1BioGRID, IntAct21903422 details
IRF7TRMT2ABioGRID, IntAct21903422 details
IRF7MAPTUniProt26402096 details
IRF7DIMT1BioGRID, IntAct30833792 details
IRF7VPS4ABioGRID, IntAct30833792 details
IRF7DNAJB11BioGRID, IntAct30833792 details
IRF7TUBA1CBioGRID, IntAct30833792 details
IRF7CCT7BioGRID, IntAct30833792 details
IRF7EFTUD2BioGRID, IntAct30833792 details
IRF7DYNC1H1BioGRID, IntAct30833792 details
IRF7TUBB2ABioGRID, IntAct30833792 details
IRF7TUBB3BioGRID, IntAct30833792 details
IRF7CHAF1BBioGRID, IntAct30833792 details
IRF7CCT2BioGRID, IntAct30833792 details
IRF7COPB1BioGRID, IntAct30833792 details
IRF7HK2BioGRID, IntAct30833792 details
IRF7KPNA2BioGRID, IntAct30833792 details
IRF7CCT4BioGRID, IntAct30833792 details
IRF7CCT8BioGRID, IntAct30833792 details
IRF7CCT3BioGRID, IntAct30833792 details
IRF7FASNBioGRID, IntAct30833792 details
IRF7CCT5BioGRID, IntAct30833792 details
IRF7QARS1BioGRID, IntAct30833792 details
IRF7MAP1BBioGRID, IntAct30833792 details
IRF7CCT6ABioGRID, IntAct30833792 details
IRF7POLD1IntAct30833792 details
IRF7CADBioGRID, IntAct30833792 details
IRF7TCP1BioGRID, IntAct30833792 details
IRF7RAF1BioGRID, IntAct30833792 details
IRF7POLR2BBioGRID30833792 details
IRF7DDX58BioGRID32513696 details