Entity Details

Primary name RYR3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15413
EntryNameRYR3_HUMAN
FullNameRyanodine receptor 3
TaxID9606
Evidenceevidence at protein level
Length4870
SequenceStatuscomplete
DateCreated2001-09-26
DateModified2021-06-02

Ontological Relatives

GenesRYR3

GO terms

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GOName
GO:0005219 ryanodine-sensitive calcium-release channel activity
GO:0005509 calcium ion binding
GO:0005516 calmodulin binding
GO:0005790 smooth endoplasmic reticulum
GO:0005886 plasma membrane
GO:0006816 calcium ion transport
GO:0015278 calcium-release channel activity
GO:0016021 integral component of membrane
GO:0016529 sarcoplasmic reticulum
GO:0030018 Z disc
GO:0030659 cytoplasmic vesicle membrane
GO:0033017 sarcoplasmic reticulum membrane
GO:0034220 ion transmembrane transport
GO:0034704 calcium channel complex
GO:0042383 sarcolemma
GO:0048763 calcium-induced calcium release activity
GO:0051209 release of sequestered calcium ion into cytosol
GO:0051289 protein homotetramerization
GO:0070588 calcium ion transmembrane transport
GO:0071277 cellular response to calcium ion
GO:0071286 cellular response to magnesium ion
GO:0071313 cellular response to caffeine
GO:0071318 cellular response to ATP
GO:1903779 regulation of cardiac conduction

Subcellular Location

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Subcellular Location
Membrane
Microsome membrane
Sarcoplasmic reticulum
Sarcoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR000699 RIH domainDomainDomain
IPR001870 B30.2/SPRY domainDomainDomain
IPR002048 EF-hand domainDomainDomain
IPR003032 Ryanodine receptor RyrDomainDomain
IPR003877 SPRY domainDomainDomain
IPR005821 Ion transport domainDomainDomain
IPR009460 Ryanodine Receptor TM 4-6DomainDomain
IPR011992 EF-hand domain pairFamilyHomologous superfamily
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR013333 Ryanodine receptorFamilyFamily
IPR013662 RyR/IP3R Homology associated domainDomainDomain
IPR014821 Inositol 1,4,5-trisphosphate/ryanodine receptorDomainDomain
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR016093 MIR motifDomainDomain
IPR035761 Ryanodine receptor, SPRY domain 1DomainDomain
IPR035762 Ryanodine receptor, SPRY domain 3DomainDomain
IPR035764 Ryanodine receptor, SPRY domain 2DomainDomain
IPR035910 RyR/IP3 receptor binding core, RIH domain superfamilyFamilyHomologous superfamily
IPR036300 Mir domain superfamilyFamilyHomologous superfamily
IPR043136 B30.2/SPRY domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB11093 Calcium citrateDrugbanksmall molecule
DB11348 Calcium PhosphateDrugbanksmall molecule
DB14481 Calcium phosphate dihydrateDrugbanksmall molecule

Interactions

5 interactions