Entity Details

Primary name VAS1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15904
EntryNameVAS1_HUMAN
FullNameV-type proton ATPase subunit S1
TaxID9606
Evidenceevidence at protein level
Length470
SequenceStatuscomplete
DateCreated2001-01-11
DateModified2021-06-02

Ontological Relatives

GenesATP6AP1

GO terms

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GOName
GO:0005524 ATP binding
GO:0005789 endoplasmic reticulum membrane
GO:0006879 cellular iron ion homeostasis
GO:0008286 insulin receptor signaling pathway
GO:0010008 endosome membrane
GO:0016021 integral component of membrane
GO:0016469 proton-transporting two-sector ATPase complex
GO:0030641 regulation of cellular pH
GO:0031267 small GTPase binding
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0033180 proton-transporting V-type ATPase, V1 domain
GO:0033181 plasma membrane proton-transporting V-type ATPase complex
GO:0033572 transferrin transport
GO:0034220 ion transmembrane transport
GO:0036295 cellular response to increased oxygen levels
GO:0045669 positive regulation of osteoblast differentiation
GO:0045780 positive regulation of bone resorption
GO:0045851 pH reduction
GO:0045921 positive regulation of exocytosis
GO:0051656 establishment of organelle localization
GO:0070062 extracellular exosome
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:1902600 proton transmembrane transport
GO:2001206 positive regulation of osteoclast development

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Endoplasmic reticulum-Golgi intermediate compartment membrane

Domains

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DomainNameCategoryType
IPR008388 ATPase, V1 complex, subunit S1FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB01133 Tiludronic acidDrugbanksmall molecule