Entity Details

Primary name NOTCH4
Entity type gene
Source Source Link

Details

PrimaryID4855
RefseqGeneNG_028190
SymbolNOTCH4
Namenotch receptor 4
Chromosome6
Location6p21.32
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-21
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsNOTC4_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000139 Golgi membrane
GO:0001569 branching involved in blood vessel morphogenesis
GO:0001709 cell fate determination
GO:0001763 morphogenesis of a branching structure
GO:0001837 epithelial to mesenchymal transition
GO:0001886 endothelial cell morphogenesis
GO:0001944 vasculature development
GO:0005112 Notch binding
GO:0005509 calcium ion binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0007221 positive regulation of transcription of Notch receptor target
GO:0009986 cell surface
GO:0030097 hemopoiesis
GO:0030154 cell differentiation
GO:0030879 mammary gland development
GO:0035278 miRNA mediated inhibition of translation
GO:0038023 signaling receptor activity
GO:0042060 wound healing
GO:0045596 negative regulation of cell differentiation
GO:0045602 negative regulation of endothelial cell differentiation
GO:0045747 positive regulation of Notch signaling pathway
GO:0045893 positive regulation of transcription, DNA-templated
GO:0060354 negative regulation of cell adhesion molecule production
GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin

Diseases

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