Entity Details

Primary name PPARD
Entity type gene
Source Source Link

Details

PrimaryID5467
RefseqGeneNG_012345
SymbolPPARD
Nameperoxisome proliferator activated receptor delta
Chromosome6
Location6p21.31
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsPPARD_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001223 transcription coactivator binding
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0003707 steroid hormone receptor activity
GO:0004879 nuclear receptor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006006 glucose metabolic process
GO:0006029 proteoglycan metabolic process
GO:0006091 generation of precursor metabolites and energy
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006629 lipid metabolic process
GO:0006631 fatty acid metabolic process
GO:0006635 fatty acid beta-oxidation
GO:0006776 vitamin A metabolic process
GO:0006915 apoptotic process
GO:0007507 heart development
GO:0007566 embryo implantation
GO:0008134 transcription factor binding
GO:0008144 drug binding
GO:0008203 cholesterol metabolic process
GO:0008270 zinc ion binding
GO:0008283 cell population proliferation
GO:0008289 lipid binding
GO:0008366 axon ensheathment
GO:0008654 phospholipid biosynthetic process
GO:0009062 fatty acid catabolic process
GO:0009749 response to glucose
GO:0009755 hormone-mediated signaling pathway
GO:0010628 positive regulation of gene expression
GO:0010887 negative regulation of cholesterol storage
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0014823 response to activity
GO:0014842 regulation of skeletal muscle satellite cell proliferation
GO:0014912 negative regulation of smooth muscle cell migration
GO:0015908 fatty acid transport
GO:0019216 regulation of lipid metabolic process
GO:0030154 cell differentiation
GO:0030308 negative regulation of cell growth
GO:0031589 cell-substrate adhesion
GO:0032966 negative regulation of collagen biosynthetic process
GO:0033189 response to vitamin A
GO:0033993 response to lipid
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0042060 wound healing
GO:0043066 negative regulation of apoptotic process
GO:0043415 positive regulation of skeletal muscle tissue regeneration
GO:0043616 keratinocyte proliferation
GO:0045600 positive regulation of fat cell differentiation
GO:0045662 negative regulation of myoblast differentiation
GO:0045684 positive regulation of epidermis development
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045923 positive regulation of fatty acid metabolic process
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046321 positive regulation of fatty acid oxidation
GO:0046697 decidualization
GO:0048662 negative regulation of smooth muscle cell proliferation
GO:0050680 negative regulation of epithelial cell proliferation
GO:0050728 negative regulation of inflammatory response
GO:0051059 NF-kappaB binding
GO:0051546 keratinocyte migration
GO:0060612 adipose tissue development
GO:0070539 linoleic acid binding
GO:0071222 cellular response to lipopolysaccharide
GO:0071456 cellular response to hypoxia
GO:0097190 apoptotic signaling pathway
GO:1902894 negative regulation of pri-miRNA transcription by RNA polymerase II
GO:1904659 glucose transmembrane transport
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000288 positive regulation of myoblast proliferation

Diseases

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Interactions

63 interactions

InteractorPartnerSourcesPublicationsLink
PPARDSMAD9BioGRID, HPRD, MINT15231748 details
PPARDKDM1ABioGRID, MINT23455924 details
PPARDPRMT3BioGRID, MINT23455924 details
PPARDSTAT3BioGRID, IntAct25814554 details
PPARDKRTAP10-7BioGRID, IntAct25416956 details
PPARDZNF837BioGRID, IntAct32296183 details
PPARDNCOA1BioGRID, IntAct15001550 15604093 15888456 16930961 21775429 details
PPARDPPARGC1ABioGRID, IntAct19596656 21775429 details
PPARDCREBBPIntAct21775429 details
PPARDNCOA2BioGRID, IntAct16930961 21775429 details
PPARDNCOR1BioGRID, HPRD, IntAct11867749 11903058 15001550 21775429 details
PPARDNR1H2BioGRID, DIP15722453 details
PPARDNR1H3BioGRID, DIP15722453 details
PPARDLMNAIntAct32814053 details
PPARDSPRED1IntAct32814053 details
PPARDHTTIntAct32814053 details
PPARDGADD45GBioGRID, HPRD10872826 details
PPARDHDAC4BioGRID12943985 details
PPARDHDAC3BioGRID, HPRD11867749 12943985 details
PPARDNCOR2BioGRID, HPRD11867749 15001550 details
PPARDHDAC1BioGRID, HPRD11867749 18037904 details
PPARDEP300BioGRID, HPRD10567538 16930961 18797151 details
PPARDGLULBioGRID15604093 details
PPARDITGB5BioGRID15604093 details
PPARDPROX1BioGRID, HPRD15604093 details
PPARDRXRABioGRID, HPRD15604093 15888456 19756148 22205725 details
PPARDPRDX6BioGRID, HPRD15604093 details
PPARDSHMT2BioGRID15604093 details
PPARDRANBP9BioGRID, HPRD15604093 details
PPARDRXRGBioGRID, HPRD15604093 22205725 details
PPARDNR0B2BioGRID, HPRD15604093 details
PPARDRXRBBioGRID, HPRD15604093 22205725 details
PPARDHSP90AA1BioGRID12962497 22939624 details
PPARDTNP1BioGRID21967852 details
PPARDKRTAP10-3BioGRID25416956 details
PPARDNCOA3BioGRID15001550 15888456 details
PPARDCEP350BioGRID15615782 details
PPARDPSMC5BioGRID15604093 details
PPARDHSP90AB1IntAct22939624 details
PPARDHDAC2BioGRID, HPRD, IntAct11867749 25241761 details
PPARDSPENBioGRID, HPRD11867749 details
PPARDPPARDBioGRID, HPRD10198642 17803688 details
PPARDRELABioGRID18037904 details
PPARDPSMG1BioGRID18793612 details
PPARDSTAT1BioGRID26504087 details
PPARDVHLBioGRID32589900 details
PPARDGADD45BHPRD10872826 details
PPARDSRCHPRD15001550 details
PPARDPEBP1HPRD15001550 details
PPARDNRIP1HPRD15001550 details
PPARDHDAC7HPRD12970571 details
PPARDDUTHPRD8910358 details
PPARDTRMT6BioGRID, IntAct26186194 28514442 details
PPARDRNF31BioGRID, IntAct26186194 28514442 details
PPARDTUBB3BioGRID, IntAct28514442 details
PPARDMDM2BioGRID, IntAct26186194 28514442 details
PPARDUBBBioGRID, IntAct26186194 28514442 details
PPARDMDM4BioGRID, IntAct26186194 28514442 details
PPARDRIC8BBioGRID26186194 details
PPARDNSMCE4ABioGRID26186194 details
PPARDPSMD14BioGRID30745168 details
PPARDTRIM25BioGRID29117863 details
PPARDDDX58BioGRID32513696 details