Entity Details

Primary name F264_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ16877
EntryNameF264_HUMAN
FullName6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4
TaxID9606
Evidenceevidence at protein level
Length469
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesPFKFB4

GO terms

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GOName
GO:0003873 6-phosphofructo-2-kinase activity
GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0006000 fructose metabolic process
GO:0006003 fructose 2,6-bisphosphate metabolic process
GO:0045821 positive regulation of glycolytic process

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active siteSiteActive site
IPR003094 Fructose-2,6-bisphosphataseFamilyFamily
IPR013078 Histidine phosphatase superfamily, clade-1FamilyFamily
IPR013079 6-phosphofructo-2-kinaseDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR029033 Histidine phosphatase superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB04395 Phosphoaminophosphonic Acid-Adenylate EsterDrugbanksmall molecule
DB04493 Fructose-6-phosphateDrugbanksmall molecule