Entity Details

Primary name BDNF
Entity type gene
Source Source Link

Details

PrimaryID627
RefseqGeneNG_011794
SymbolBDNF
Namebrain derived neurotrophic factor
Chromosome11
Location11p14.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1991-12-06
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsBDNF_HUMAN

GO terms

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GOName
GO:0005163 nerve growth factor receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007202 activation of phospholipase C activity
GO:0007399 nervous system development
GO:0007411 axon guidance
GO:0007416 synapse assembly
GO:0007422 peripheral nervous system development
GO:0007613 memory
GO:0008021 synaptic vesicle
GO:0008083 growth factor activity
GO:0010832 negative regulation of myotube differentiation
GO:0010976 positive regulation of neuron projection development
GO:0016607 nuclear speck
GO:0021675 nerve development
GO:0030424 axon
GO:0030425 dendrite
GO:0031547 brain-derived neurotrophic factor receptor signaling pathway
GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0038180 nerve growth factor signaling pathway
GO:0043524 negative regulation of neuron apoptotic process
GO:0045664 regulation of neuron differentiation
GO:0048011 neurotrophin TRK receptor signaling pathway
GO:0048471 perinuclear region of cytoplasm
GO:0048668 collateral sprouting
GO:0048672 positive regulation of collateral sprouting
GO:0048812 neuron projection morphogenesis
GO:0050804 modulation of chemical synaptic transmission
GO:0051965 positive regulation of synapse assembly
GO:1900122 positive regulation of receptor binding
GO:1903997 positive regulation of non-membrane spanning protein tyrosine kinase activity
GO:2000008 regulation of protein localization to cell surface
GO:2001234 negative regulation of apoptotic signaling pathway

Diseases

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Interactions

72 interactions

InteractorPartnerSourcesPublicationsLink
BDNFNTF3BioGRID, HPRD, IntAct7703225 details
BDNFJUNBBioGRID, IntAct21988832 details
BDNFF11RBioGRID, IntAct21988832 details
BDNFINPP5KBioGRID, IntAct21988832 details
BDNFAGO3BioGRID, IntAct21988832 details
BDNFNTF4BioGRID, IntAct10631974 25241761 29997244 details
BDNFSORCS2bhf-ucl24908487 details
BDNFFAM209ABioGRID, IntAct32296183 details
BDNFSORT1BioGRID, DIP, HPRD, IntAct15987945 19122660 20159974 21357693 32296183 details
BDNFGPR152BioGRID, IntAct32296183 details
BDNFCREB3IntAct31515488 details
BDNFCYTH1IntAct32814053 details
BDNFFKBP6IntAct32814053 details
BDNFTXNIntAct32814053 details
BDNFPRPS1IntAct32814053 details
BDNFPRKACAIntAct32814053 details
BDNFLBPIntAct32814053 details
BDNFHOXA3IntAct32814053 details
BDNFFYNIntAct32814053 details
BDNFFUT2IntAct32814053 details
BDNFEPHX1IntAct32814053 details
BDNFDNASE1L1IntAct32814053 details
BDNFCTNNB1IntAct32814053 details
BDNFCRMP1IntAct32814053 details
BDNFCAMK2AIntAct32814053 details
BDNFMRPL49IntAct32814053 details
BDNFAGERIntAct32814053 details
BDNFBTBD1IntAct32814053 details
BDNFGALIntAct32814053 details
BDNFAK3IntAct32814053 details
BDNFHCSTIntAct32814053 details
BDNFEXOC5IntAct32814053 details
BDNFKAT5IntAct32814053 details
BDNFDHRS9IntAct32814053 details
BDNFUBE3CIntAct32814053 details
BDNFSNX20IntAct32814053 details
BDNFMRAP2IntAct32814053 details
BDNFCCDC32IntAct32814053 details
BDNFHSFY2IntAct32814053 details
BDNFHSFY1IntAct32814053 details
BDNFCORO6IntAct32814053 details
BDNFAPH1BIntAct32814053 details
BDNFWDCPIntAct32814053 details
BDNFTLE6IntAct32814053 details
BDNFRUSF1IntAct32814053 details
BDNFSLC41A3IntAct32814053 details
BDNFPLPPR1IntAct32814053 details
BDNFANKHD1-EIF4EBP3IntAct32814053 details
BDNFANKHD1IntAct32814053 details
BDNFADAMTSL4IntAct32814053 details
BDNFSLC44A5IntAct32814053 details
BDNFZFC3H1IntAct32814053 details
BDNFCDK5IntAct32814053 details
BDNFAPPBioGRID, IntAct21832049 32814053 details
BDNFNTRK2BioGRID, HPRD11855816 21651720 9312147 details
BDNFRHOUBioGRID26598620 details
BDNFHAP1BioGRID21357693 details
BDNFLRP1BioGRID7537086 details
BDNFDNMT1BioGRID25476119 details
BDNFTET1BioGRID25476119 details
BDNFMBD2BioGRID25476119 details
BDNFNCAM1HPRD10760298 details
BDNFESR1HPRD11923430 details
BDNFNOS3HPRD10493752 details
BDNFMBTPS1HPRD9990022 details
BDNFCPEHPRD15664176 details
BDNFBDNFHPRD7961712 8174548 details
BDNFCADPS2HPRD14715936 details
BDNFH1-1BioGRID, IntAct30021884 details
BDNFLOC102724334BioGRID, IntAct30021884 details
BDNFELAVL1BioGRID19322201 details
BDNFHNRNPH1BioGRID26760575 details