Entity Details

Primary name SCX
Entity type gene
Source Source Link

Details

PrimaryID642658
RefseqGene
SymbolSCX
Namescleraxis bHLH transcription factor
Chromosome8
Location8q24.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2005-11-30
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSCX_HUMAN

GO terms

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GOName
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001707 mesoderm formation
GO:0001894 tissue homeostasis
GO:0001958 endochondral ossification
GO:0002062 chondrocyte differentiation
GO:0003179 heart valve morphogenesis
GO:0003188 heart valve formation
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0006351 transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008284 positive regulation of cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0030154 cell differentiation
GO:0030199 collagen fibril organization
GO:0030509 BMP signaling pathway
GO:0032502 developmental process
GO:0032967 positive regulation of collagen biosynthetic process
GO:0035914 skeletal muscle cell differentiation
GO:0035989 tendon development
GO:0035990 tendon cell differentiation
GO:0035992 tendon formation
GO:0035993 deltoid tuberosity development
GO:0043066 negative regulation of apoptotic process
GO:0043425 bHLH transcription factor binding
GO:0043565 sequence-specific DNA binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046983 protein dimerization activity
GO:0048706 embryonic skeletal system development
GO:0060008 Sertoli cell differentiation
GO:0060325 face morphogenesis
GO:0061035 regulation of cartilage development
GO:0061036 positive regulation of cartilage development
GO:0061056 sclerotome development
GO:0070888 E-box binding
GO:0071260 cellular response to mechanical stimulus
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:2000543 positive regulation of gastrulation

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
SCXNCK2BioGRID, IntAct32296183 details
SCXMYF5BioGRID, IntAct32296183 details
SCXTCF4BioGRID, IntAct32296183 details
SCXTCF3BioGRID9050988 details
SCXSOX9BioGRID19828133 details