Entity Details

Primary name P2RY12
Entity type gene
Source Source Link

Details

PrimaryID64805
RefseqGeneNG_016019
SymbolP2RY12
Namepurinergic receptor P2Y12
Chromosome3
Location3q25.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-03-19
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsP2Y12_HUMAN

GO terms

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GOName
GO:0001609 G protein-coupled adenosine receptor activity
GO:0001621 G protein-coupled ADP receptor activity
GO:0005739 mitochondrion
GO:0005886 plasma membrane
GO:0005901 caveola
GO:0006930 substrate-dependent cell migration, cell extension
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0007202 activation of phospholipase C activity
GO:0007599 hemostasis
GO:0009897 external side of plasma membrane
GO:0009925 basal plasma membrane
GO:0009986 cell surface
GO:0010700 negative regulation of norepinephrine secretion
GO:0016021 integral component of membrane
GO:0019722 calcium-mediated signaling
GO:0021808 cytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration
GO:0030030 cell projection organization
GO:0030032 lamellipodium assembly
GO:0030168 platelet activation
GO:0031224 intrinsic component of membrane
GO:0031253 cell projection membrane
GO:0033626 positive regulation of integrin activation by cell surface receptor linked signal transduction
GO:0033630 positive regulation of cell adhesion mediated by integrin
GO:0035585 calcium-mediated signaling using extracellular calcium source
GO:0043270 positive regulation of ion transport
GO:0043491 protein kinase B signaling
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity
GO:0044298 cell body membrane
GO:0045028 G protein-coupled purinergic nucleotide receptor activity
GO:0045596 negative regulation of cell differentiation
GO:0048678 response to axon injury
GO:0050920 regulation of chemotaxis
GO:0050921 positive regulation of chemotaxis
GO:0051897 positive regulation of protein kinase B signaling
GO:0051924 regulation of calcium ion transport
GO:0070527 platelet aggregation
GO:0070588 calcium ion transmembrane transport
GO:0071318 cellular response to ATP
GO:0071805 potassium ion transmembrane transport
GO:0150063 visual system development
GO:1900029 positive regulation of ruffle assembly
GO:1904124 microglial cell migration
GO:1904139 regulation of microglial cell migration
GO:1904141 positive regulation of microglial cell migration

Diseases

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Interactions

61 interactions

InteractorPartnerSourcesPublicationsLink
P2RY12P2RY12DIP16835302 details
P2RY12GNAI2HPRD8554519 details
P2RY12MRS2BioGRID, IntAct26186194 28514442 details
P2RY12BLVRABioGRID, IntAct28514442 details
P2RY12TSPAN15BioGRID, IntAct26186194 28514442 details
P2RY12TNPO3BioGRID, IntAct26186194 28514442 details
P2RY12C19orf25BioGRID, IntAct26186194 28514442 details
P2RY12SLC39A1BioGRID, IntAct26186194 28514442 details
P2RY12GEMIN8BioGRID, IntAct26186194 28514442 details
P2RY12SACM1LBioGRID, IntAct26186194 28514442 details
P2RY12TM9SF3BioGRID, IntAct28514442 details
P2RY12ACAD9BioGRID, IntAct26186194 28514442 details
P2RY12GOLPH3BioGRID, IntAct26186194 28514442 details
P2RY12YIPF3BioGRID, IntAct26186194 28514442 details
P2RY12TTYH3BioGRID, IntAct26186194 28514442 details
P2RY12XPO4BioGRID, IntAct26186194 28514442 details
P2RY12PTDSS2BioGRID, IntAct28514442 details
P2RY12ECSITBioGRID, IntAct26186194 28514442 details
P2RY12RNF170BioGRID, IntAct26186194 28514442 details
P2RY12CRELD1BioGRID, IntAct26186194 28514442 details
P2RY12GEMIN6BioGRID, IntAct26186194 28514442 details
P2RY12LMBR1BioGRID, IntAct26186194 28514442 details
P2RY12GOLGA5BioGRID, IntAct26186194 28514442 details
P2RY12MFSD8BioGRID, IntAct26186194 28514442 details
P2RY12TMEM161BBioGRID, IntAct26186194 28514442 details
P2RY12ARL10BioGRID, IntAct26186194 28514442 details
P2RY12FITM2BioGRID, IntAct28514442 details
P2RY12CERS5BioGRID, IntAct26186194 28514442 details
P2RY12KIAA2013BioGRID, IntAct26186194 28514442 details
P2RY12DYMBioGRID, IntAct26186194 28514442 details
P2RY12TMPPEBioGRID, IntAct26186194 28514442 details
P2RY12CERS6BioGRID, IntAct26186194 28514442 details
P2RY12PTRHD1BioGRID, IntAct28514442 details
P2RY12TMEM164BioGRID, IntAct26186194 28514442 details
P2RY12TTC39ABioGRID, IntAct26186194 28514442 details
P2RY12EBPBioGRID, IntAct26186194 28514442 details
P2RY12ITPR2BioGRID, IntAct26186194 28514442 details
P2RY12CAV1BioGRID, IntAct26186194 28514442 details
P2RY12ATP5PBBioGRID, IntAct26186194 28514442 details
P2RY12ACP2BioGRID, IntAct26186194 28514442 details
P2RY12ATP5F1BBioGRID, IntAct26186194 28514442 details
P2RY12APOBBioGRID, IntAct26186194 28514442 details
P2RY12ND1BioGRID, IntAct26186194 28514442 details
P2RY12COX1BioGRID, IntAct26186194 28514442 details
P2RY12ATP5PDBioGRID, IntAct28514442 details
P2RY12ARL6IP5BioGRID, IntAct26186194 28514442 details
P2RY12GPR89BIntAct28514442 details
P2RY12GPR89ABioGRID, IntAct26186194 28514442 details
P2RY12VKORC1L1BioGRID26186194 details
P2RY12SAAL1BioGRID26186194 details
P2RY12GEMIN4BioGRID26186194 details
P2RY12PALS2BioGRID26186194 details
P2RY12IPO11BioGRID26186194 details
P2RY12RMND1BioGRID26186194 details
P2RY12DDX20BioGRID26186194 details
P2RY12LGALS3BioGRID26186194 details
P2RY12SLC30A7BioGRID26186194 details
P2RY12RFT1BioGRID26186194 details
P2RY12ALG10BioGRID26186194 details
P2RY12CMTM6BioGRID26186194 details
P2RY12BRI3BPBioGRID26186194 details