Entity Details

Primary name STX1A
Entity type gene
Source Source Link

Details

PrimaryID6804
RefseqGeneNG_013360
SymbolSTX1A
Namesyntaxin 1A
Chromosome7
Location7q11.23
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1995-11-28
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsSTX1A_HUMAN

GO terms

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GOName
GO:0000149 SNARE binding
GO:0001956 positive regulation of neurotransmitter secretion
GO:0005484 SNAP receptor activity
GO:0005576 extracellular region
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006836 neurotransmitter transport
GO:0006886 intracellular protein transport
GO:0006887 exocytosis
GO:0006906 vesicle fusion
GO:0007269 neurotransmitter secretion
GO:0008021 synaptic vesicle
GO:0008076 voltage-gated potassium channel complex
GO:0009629 response to gravity
GO:0010701 positive regulation of norepinephrine secretion
GO:0010807 regulation of synaptic vesicle priming
GO:0012505 endomembrane system
GO:0014069 postsynaptic density
GO:0016021 integral component of membrane
GO:0016079 synaptic vesicle exocytosis
GO:0016081 synaptic vesicle docking
GO:0016925 protein sumoylation
GO:0017156 calcium-ion regulated exocytosis
GO:0019221 cytokine-mediated signaling pathway
GO:0019855 calcium channel inhibitor activity
GO:0019869 chloride channel inhibitor activity
GO:0019900 kinase binding
GO:0019904 protein domain specific binding
GO:0030073 insulin secretion
GO:0030141 secretory granule
GO:0030285 integral component of synaptic vesicle membrane
GO:0030424 axon
GO:0031201 SNARE complex
GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane
GO:0031965 nuclear membrane
GO:0032028 myosin head/neck binding
GO:0032940 secretion by cell
GO:0033605 positive regulation of catecholamine secretion
GO:0035493 SNARE complex assembly
GO:0042641 actomyosin
GO:0042802 identical protein binding
GO:0043005 neuron projection
GO:0043008 ATP-dependent protein binding
GO:0044325 transmembrane transporter binding
GO:0044877 protein-containing complex binding
GO:0045048 protein insertion into ER membrane
GO:0045956 positive regulation of calcium ion-dependent exocytosis
GO:0047485 protein N-terminus binding
GO:0048278 vesicle docking
GO:0048306 calcium-dependent protein binding
GO:0048488 synaptic vesicle endocytosis
GO:0048787 presynaptic active zone membrane
GO:0050796 regulation of insulin secretion
GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex
GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex
GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex
GO:0098978 glutamatergic synapse
GO:0099056 integral component of presynaptic membrane
GO:2000463 positive regulation of excitatory postsynaptic potential

Diseases

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Interactions

184 interactions

InteractorPartnerSourcesPublicationsLink
STX1ASNAP25BioGRID, HPRD, IntAct, MINT, UniProt10195194 10373452 10449403 10954418 11509230 11524423 11832227 16169070 17363971 20489724 20798282 30610939 7553862 7622514 7768895 7961655 8663154 9556632 9852078 details
STX1ATRDMT1BioGRID, HPRD, IntAct16169070 details
STX1AVIMBioGRID, HPRD, IntAct16169070 details
STX1ACCSER2BioGRID, HPRD, IntAct16169070 details
STX1ASNAP23BioGRID, HPRD, IntAct12209004 12651853 12828989 24722188 26359495 8663154 9168999 9852078 details
STX1ASNAP29BioGRID, HPRD, IntAct24722188 26359495 9852078 details
STX1APSMA3BioGRID, IntAct24722188 details
STX1ANAPBBioGRID, IntAct24722188 32296183 details
STX1ASTX1ABioGRID, HPRD, IntAct10100611 10194441 10449403 10746715 24722188 32296183 8108429 9045631 details
STX1ATXLNABioGRID, HPRD, IntAct12558796 24722188 32296183 details
STX1ATXLNBBioGRID, HPRD, IntAct15184072 24722188 details
STX1AMALBioGRID, IntAct32296183 details
STX1ASMIM1BioGRID, IntAct32296183 details
STX1AUPK1BBioGRID, IntAct32296183 details
STX1ATMEM128BioGRID, IntAct32296183 details
STX1AC4orf3BioGRID, IntAct32296183 details
STX1ASMIM3BioGRID, IntAct32296183 details
STX1APLP1BioGRID, IntAct32296183 details
STX1AZNF250BioGRID, IntAct32296183 details
STX1ARAB3IL1BioGRID, IntAct32296183 details
STX1ASEC22ABioGRID, IntAct32296183 details
STX1ACYB5BBioGRID, IntAct32296183 details
STX1ASERP2BioGRID, IntAct32296183 details
STX1APLPP6BioGRID, IntAct32296183 details
STX1APNLIPRP1BioGRID, IntAct32296183 details
STX1ANKG7BioGRID, IntAct32296183 details
STX1ATNFBioGRID, IntAct32296183 details
STX1AVAMP5BioGRID, IntAct24722188 32296183 details
STX1ARTP2BioGRID, IntAct32296183 details
STX1ASTX2BioGRID, IntAct32296183 details
STX1AVAMP4BioGRID, IntAct32296183 details
STX1AVAMP3BioGRID, IntAct32296183 details
STX1ASTX11BioGRID, IntAct32296183 details
STX1ATCEANCBioGRID, IntAct32296183 details
STX1AZNF557BioGRID, IntAct32296183 details
STX1AZFPL1BioGRID, IntAct32296183 details
STX1AFAM3CBioGRID, IntAct32296183 details
STX1ASTX7BioGRID, IntAct32296183 details
STX1ASNAP47BioGRID, IntAct32296183 details
STX1ANINJ2BioGRID, IntAct32296183 details
STX1AAPOL2BioGRID, IntAct32296183 details
STX1AAPOL3BioGRID, IntAct32296183 details
STX1AAGTRAPBioGRID, IntAct32296183 details
STX1ADDX49BioGRID, IntAct32296183 details
STX1AZNF835BioGRID, IntAct32296183 details
STX1ACMTM7BioGRID, IntAct32296183 details
STX1AZNF479BioGRID, IntAct32296183 details
STX1ABET1BioGRID, IntAct32296183 details
STX1AVAMP1BioGRID, HPRD, IntAct12093152 32296183 details
STX1AGIMAP5BioGRID, IntAct32296183 details
STX1AZNF136BioGRID, IntAct32296183 details
STX1AZNF696BioGRID, IntAct32296183 details
STX1AGOSR2BioGRID, IntAct32296183 details
STX1AHMOX1BioGRID, IntAct32296183 details
STX1AEMDBioGRID, IntAct32296183 details
STX1AVTI1BBioGRID, IntAct32296183 details
STX1AZNF12BioGRID, IntAct32296183 details
STX1ATMEM60BioGRID, IntAct32296183 details
STX1APLNBioGRID, IntAct32296183 details
STX1AGIMAP1BioGRID, IntAct32296183 details
STX1ATMEM120ABioGRID, IntAct32296183 details
STX1AMMGT1BioGRID, IntAct32296183 details
STX1AEBAG9BioGRID, IntAct32296183 details
STX1AARL13BBioGRID, IntAct32296183 details
STX1ARNF4BioGRID, IntAct32296183 details
STX1ASTX4BioGRID, IntAct32296183 details
STX1ATMEM222BioGRID, IntAct32296183 details
STX1AZNF441BioGRID, IntAct32296183 details
STX1ACD81BioGRID, IntAct32296183 details
STX1AJAGN1BioGRID, IntAct32296183 details
STX1ASTX8BioGRID, HPRD, IntAct11101518 32296183 details
STX1AAIG1BioGRID, IntAct32296183 details
STX1ATMEM14CBioGRID, IntAct32296183 details
STX1AKIFC3BioGRID, IntAct32296183 details
STX1ASTX12BioGRID, IntAct32296183 details
STX1ANRMBioGRID, IntAct32296183 details
STX1AVSTM4BioGRID, IntAct32296183 details
STX1AANKRD46BioGRID, IntAct32296183 details
STX1AETNK2BioGRID, IntAct32296183 details
STX1AERG28BioGRID, IntAct32296183 details
STX1AABI3BioGRID, IntAct32296183 details
STX1AZNF440BioGRID, IntAct32296183 details
STX1AUSE1BioGRID, IntAct32296183 details
STX1AUBTFL1BioGRID, IntAct32296183 details
STX1APGAP2BioGRID, IntAct32296183 details
STX1ASTX6BioGRID, IntAct32296183 details
STX1ACLN6BioGRID, IntAct32296183 details
STX1APLPP4BioGRID, IntAct32296183 details
STX1ASTX16BioGRID, IntAct32296183 details
STX1ATMEM41ABioGRID, IntAct32296183 details
STX1AVAMP2BioGRID, HPRD, IntAct, UniProt10100611 10449403 11832227 12093152 20798282 32296183 7553862 9030619 details
STX1ASTX3BioGRID, IntAct32296183 details
STX1ATMEM254BioGRID, IntAct32296183 details
STX1ACLEC1ABioGRID, IntAct32296183 details
STX1ASNORCBioGRID, IntAct32296183 details
STX1AZNF785BioGRID, IntAct32296183 details
STX1ASTX5BioGRID, IntAct32296183 details
STX1AAOC3BioGRID, IntAct32296183 details
STX1ATRAF3IP3BioGRID, IntAct32296183 details
STX1AGPM6BBioGRID, IntAct32296183 details
STX1ABNIP1BioGRID, IntAct32296183 details
STX1ATMEM199BioGRID, IntAct32296183 details
STX1ATMEM100BioGRID, IntAct32296183 details
STX1AAQP3BioGRID, IntAct32296183 details
STX1ABLOC1S6BioGRID, IntAct32296183 details
STX1ASTX10BioGRID, IntAct32296183 details
STX1AMALLBioGRID, IntAct32296183 details
STX1AZNF707BioGRID, IntAct32296183 details
STX1AMIPBioGRID, IntAct32296183 details
STX1AZNF490BioGRID, IntAct32296183 details
STX1ABTN2A2BioGRID, IntAct32296183 details
STX1ACDC37BioGRID, IntAct32296183 details
STX1ASEC22BBioGRID, DIP, IntAct24705552 32296183 details
STX1AAARDBioGRID, IntAct32296183 details
STX1ASERP1BioGRID, IntAct32296183 details
STX1ATSGA10IPBioGRID, IntAct32296183 details
STX1ARMDN2BioGRID, IntAct32296183 details
STX1ASTXBP1BioGRID, HPRD, IntAct10194441 10449403 10746715 12093152 12519779 12963086 15563604 17363971 31413325 7553862 8108429 9045631 details
STX1AUNC13BBioGRID, HPRD8999968 details
STX1ASCNN1GBioGRID, HPRD10409621 12562778 14996668 details
STX1AVAMP7BioGRID, HPRD12853575 details
STX1ASTXBP5BioGRID, HPRD12832401 9620695 details
STX1AATP6V1B1BioGRID12651853 details
STX1AVAPBBioGRID12651853 24885147 details
STX1ASYTL4BioGRID, HPRD12101244 12590134 details
STX1ARNF40BioGRID12121982 details
STX1ACPLX1BioGRID, HPRD10449403 11832227 12200427 7553862 details
STX1ACFTRBioGRID, HPRD12209004 9384384 details
STX1ANAPABioGRID, HPRD7553862 7622514 details
STX1ASYT1BioGRID, HPRD10397765 11438523 9010211 details
STX1ASLC6A4BioGRID, HPRD12175857 24878716 details
STX1ASLC6A1BioGRID, HPRD11017172 11960023 9698305 details
STX1AVAMP8BioGRID, HPRD11112705 details
STX1ACDK5BioGRID, HPRD9478941 details
STX1ASLC6A3BioGRID, HPRD15202772 18617632 25774383 details
STX1AKCNB1BioGRID, HPRD12403834 15518587 22411134 details
STX1AVPS18BioGRID, HPRD14623309 17027648 details
STX1AVPS16BioGRID17027648 details
STX1AVPS11BioGRID, HPRD14623309 17027648 details
STX1AUBE2IBioGRID32296183 details
STX1AC1GALT1BioGRID32296183 details
STX1ACXCL16BioGRID32296183 details
STX1AGOLM2BioGRID32296183 details
STX1ATSNARE1BioGRID32296183 details
STX1ASTXBP2HPRD7768895 9045631 details
STX1ASNPHHPRD10707983 details
STX1AMDM2IntAct20195357 details
STX1ASTXBP6BioGRID, HPRD, IntAct12145319 28514442 details
STX1ASNCAUniProt20798282 details
STX1ADISC1IntAct31413325 details
STX1ASCNN1ABioGRID, HPRD10409621 12562778 14996668 details
STX1ASCNN1BBioGRID, HPRD11845306 12562778 14996668 details
STX1ACPLX2BioGRID10449403 details
STX1ASYPBioGRID7553862 details
STX1ASLC6A9BioGRID, HPRD10722844 details
STX1ASLC6A5BioGRID, HPRD10722844 15276154 details
STX1ASLC6A2BioGRID, HPRD12629174 17032905 details
STX1ASYT4HPRD10397765 details
STX1ADAPK1HPRD12730201 details
STX1ASEPTIN2HPRD10321247 details
STX1AAPBA1HPRD9395480 details
STX1ASEPTIN5HPRD10321247 details
STX1ARAB27AHPRD12101244 details
STX1ASYT7HPRD7791877 details
STX1ACACNA1DHPRD10468580 details
STX1ACSNK2A1HPRD10844023 9930733 details
STX1ACSNK2A2HPRD10844023 9930733 details
STX1ANSFHPRD7622514 details
STX1AABCC9HPRD15339904 details
STX1ASDCBPHPRD15276154 details
STX1AATP4BHPRD12651853 details
STX1ARIMS1HPRD11438522 details
STX1AHTTIntAct17500595 details
STX1ANUFIP1BioGRID, IntAct26186194 28514442 details
STX1ADGUOKBioGRID, IntAct26186194 28514442 details
STX1AHAX1BioGRID, IntAct26186194 28514442 details
STX1ADNAAF2BioGRID, IntAct26186194 28514442 details
STX1AOIP5BioGRID, IntAct26186194 28514442 details
STX1ACDR2BioGRID, IntAct28514442 details
STX1ADPP8BioGRID, IntAct30021884 details
STX1APPP1CABioGRID17274640 details
STX1ATNIP2BioGRID27609421 details
STX1ACHMP4CBioGRID31586073 details
STX1AAPEX1BioGRID28986522 details