Entity Details

Primary name CCR2
Entity type gene
Source Source Link

Details

PrimaryID729230
RefseqGeneNG_021428
SymbolCCR2
NameC-C motif chemokine receptor 2
Chromosome3
Location3p21.31
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2006-07-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCCR2_HUMAN

GO terms

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GOName
GO:0001974 blood vessel remodeling
GO:0002407 dendritic cell chemotaxis
GO:0002724 regulation of T cell cytokine production
GO:0002827 positive regulation of T-helper 1 type immune response
GO:0002829 negative regulation of type 2 immune response
GO:0004950 chemokine receptor activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006874 cellular calcium ion homeostasis
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0006968 cellular defense response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007194 negative regulation of adenylate cyclase activity
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007259 receptor signaling pathway via JAK-STAT
GO:0009611 response to wounding
GO:0009897 external side of plasma membrane
GO:0010574 regulation of vascular endothelial growth factor production
GO:0010820 positive regulation of T cell chemotaxis
GO:0016021 integral component of membrane
GO:0016032 viral process
GO:0016493 C-C chemokine receptor activity
GO:0016525 negative regulation of angiogenesis
GO:0019221 cytokine-mediated signaling pathway
GO:0019233 sensory perception of pain
GO:0019722 calcium-mediated signaling
GO:0019725 cellular homeostasis
GO:0019957 C-C chemokine binding
GO:0030425 dendrite
GO:0031727 CCR2 chemokine receptor binding
GO:0032729 positive regulation of interferon-gamma production
GO:0032743 positive regulation of interleukin-2 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0035696 monocyte extravasation
GO:0035705 T-helper 17 cell chemotaxis
GO:0042802 identical protein binding
GO:0043025 neuronal cell body
GO:0043204 perikaryon
GO:0043310 negative regulation of eosinophil degranulation
GO:0045580 regulation of T cell differentiation
GO:0046641 positive regulation of alpha-beta T cell proliferation
GO:0048471 perinuclear region of cytoplasm
GO:0050727 regulation of inflammatory response
GO:0050729 positive regulation of inflammatory response
GO:0050870 positive regulation of T cell activation
GO:0051968 positive regulation of synaptic transmission, glutamatergic
GO:0060326 cell chemotaxis
GO:0070098 chemokine-mediated signaling pathway
GO:0090026 positive regulation of monocyte chemotaxis
GO:0090265 positive regulation of immune complex clearance by monocytes and macrophages
GO:0090594 inflammatory response to wounding
GO:0120162 positive regulation of cold-induced thermogenesis
GO:1904783 positive regulation of NMDA glutamate receptor activity
GO:1905517 macrophage migration
GO:2000412 positive regulation of thymocyte migration
GO:2000439 positive regulation of monocyte extravasation
GO:2000451 positive regulation of CD8-positive, alpha-beta T cell extravasation
GO:2000464 positive regulation of astrocyte chemotaxis
GO:2000473 positive regulation of hematopoietic stem cell migration

Diseases

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Interactions

52 interactions

InteractorPartnerSourcesPublicationsLink
CCR2NUP85MINT25283965 details
CCR2ARL6IP5BioGRID, MINT28298427 details
CCR2CD81BioGRID, MINT28298427 details
CCR2CD59BioGRID, MINT28298427 details
CCR2CACYBPBioGRID, MINT28298427 details
CCR2B3GAT3BioGRID, MINT28298427 details
CCR2ATP2B1BioGRID, MINT28298427 details
CCR2APPBioGRID, MINT28298427 details
CCR2HERPUD1BioGRID, MINT28298427 details
CCR2CLPTM1BioGRID, MINT28298427 details
CCR2DMWDBioGRID, MINT28298427 details
CCR2S1PR5BioGRID, MINT28298427 details
CCR2HMOX2BioGRID, MINT28298427 details
CCR2GOT1BioGRID, MINT28298427 details
CCR2WLSBioGRID, MINT28298427 details
CCR2GPR161BioGRID, MINT28298427 details
CCR2EMC10BioGRID, MINT28298427 details
CCR2CDIP1BioGRID, MINT28298427 details
CCR2ERGIC3BioGRID, MINT28298427 details
CCR2NDFIP1BioGRID, MINT28298427 details
CCR2TECPR2BioGRID, MINT28298427 details
CCR2JPH3BioGRID, MINT28298427 details
CCR2SCG5BioGRID, MINT28298427 details
CCR2RGRBioGRID, MINT28298427 details
CCR2RTN3BioGRID, MINT28298427 details
CCR2RHOGBioGRID, MINT28298427 details
CCR2PCMT1BioGRID, MINT28298427 details
CCR2PTPN9BioGRID, MINT28298427 details
CCR2PLLPBioGRID, MINT28298427 details
CCR2BLOC1S6BioGRID, MINT28298427 details
CCR2NOTCH2BioGRID, MINT28298427 details
CCR2NTNG2BioGRID, MINT28298427 details
CCR2SUMO1BioGRID, MINT28298427 details
CCR2SLC2A1BioGRID, MINT28298427 details
CCR2SRSF5BioGRID, MINT28298427 details
CCR2SLC41A3BioGRID, MINT28298427 details
CCR2TMEM199BioGRID, MINT28298427 details
CCR2TMEM161ABioGRID, MINT28298427 details
CCR2TSPAN7BioGRID, MINT28298427 details
CCR2SVOPBioGRID, MINT28298427 details
CCR2TMEM63ABioGRID, MINT28298427 details
CCR2CCL11HPRD11264152 details
CCR2CCR5HPRD11350939 details
CCR2CCL13HPRD12149192 9195948 details
CCR2CCL16HPRD11470772 details
CCR2CCL8HPRD12149192 9115216 details
CCR2TPST1HPRD17558413 details
CCR2TPST2HPRD17558413 details
CCR2JAK2HPRD9670957 details
CCR2CCL2HPRD10529171 9287323 details
CCR2CCL7HPRD8530354 details
CCR2POTEEBioGRID, IntAct28514442 details