Entity Details

Primary name TYROBP
Entity type gene
Source Source Link

Details

PrimaryID7305
RefseqGeneNG_009304
SymbolTYROBP
Nametransmembrane immune signaling adaptor TYROBP
Chromosome19
Location19q13.12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-06-25
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsTYOBP_HUMAN

GO terms

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GOName
GO:0002222 stimulatory killer cell immunoglobulin-like receptor signaling pathway
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0002274 myeloid leukocyte activation
GO:0002282 microglial cell activation involved in immune response
GO:0002283 neutrophil activation involved in immune response
GO:0005102 signaling receptor binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006968 cellular defense response
GO:0007165 signal transduction
GO:0009986 cell surface
GO:0010628 positive regulation of gene expression
GO:0016021 integral component of membrane
GO:0030036 actin cytoskeleton organization
GO:0030316 osteoclast differentiation
GO:0030667 secretory granule membrane
GO:0030889 negative regulation of B cell proliferation
GO:0030900 forebrain development
GO:0032693 negative regulation of interleukin-10 production
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032755 positive regulation of interleukin-6 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0032816 positive regulation of natural killer cell activation
GO:0032911 negative regulation of transforming growth factor beta1 production
GO:0032930 positive regulation of superoxide anion generation
GO:0034241 positive regulation of macrophage fusion
GO:0035556 intracellular signal transduction
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043277 apoptotic cell clearance
GO:0043312 neutrophil degranulation
GO:0045087 innate immune response
GO:0046872 metal ion binding
GO:0048678 response to axon injury
GO:0050776 regulation of immune response
GO:0050821 protein stabilization
GO:0097190 apoptotic signaling pathway
GO:0110090 positive regulation of hippocampal neuron apoptotic process
GO:1900272 negative regulation of long-term synaptic potentiation
GO:1901216 positive regulation of neuron death
GO:1902685 positive regulation of receptor localization to synapse
GO:1904151 positive regulation of microglial cell mediated cytotoxicity
GO:2000010 positive regulation of protein localization to cell surface
GO:2001206 positive regulation of osteoclast development

Diseases

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