Entity Details

Primary name RUNX3
Entity type gene
Source Source Link

Details

PrimaryID864
RefseqGene
SymbolRUNX3
NameRUNX family transcription factor 3
Chromosome1
Location1p36.11
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-11-09
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsRUNX3_HUMAN

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001503 ossification
GO:0002062 chondrocyte differentiation
GO:0003700 DNA-binding transcription factor activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006468 protein phosphorylation
GO:0016513 core-binding factor complex
GO:0030097 hemopoiesis
GO:0030182 neuron differentiation
GO:0043231 intracellular membrane-bounded organelle
GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation
GO:0043378 positive regulation of CD8-positive, alpha-beta T cell differentiation
GO:0045595 regulation of cell differentiation
GO:0045786 negative regulation of cell cycle
GO:0045893 positive regulation of transcription, DNA-templated
GO:0048935 peripheral nervous system neuron development
GO:0050680 negative regulation of epithelial cell proliferation
GO:0071559 response to transforming growth factor beta
GO:1990837 sequence-specific double-stranded DNA binding

Diseases

Show/Hide Table

Interactions

50 interactions

InteractorPartnerSourcesPublicationsLink
RUNX3TLE1BioGRID, HPRD, IntAct9751710 details
RUNX3GUCD1BioGRID, IntAct32296183 details
RUNX3CBFBBioGRID, HPRD, IntAct15138260 23333304 31253590 32296183 7622058 details
RUNX3SP110BioGRID, IntAct20211142 details
RUNX3YAP1BioGRID10228168 details
RUNX3NOTCH1BioGRID19800882 details
RUNX3MYCNBioGRID23851507 details
RUNX3TP53BioGRID20353948 details
RUNX3GLI1BioGRID31278361 details
RUNX3CTNNB1IntAct18772112 details
RUNX3TCF7L2IntAct18772112 details
RUNX3TCF7IntAct18772112 details
RUNX3BRD2IntAct24229708 details
RUNX3HDAC4HPRD, IntAct15138260 24229708 details
RUNX3HDAC5BioGRID, HPRD, IntAct15138260 24229708 details
RUNX3EP300BioGRID, HPRD, IntAct15138260 24229708 details
RUNX3SMAD3BioGRID, HPRD10531362 15138260 27497248 details
RUNX3SMAD1BioGRID10531362 details
RUNX3SMAD2BioGRID10531362 details
RUNX3SMAD5BioGRID10531362 details
RUNX3SUV39H1BioGRID16652147 details
RUNX3SMURF1BioGRID, HPRD15138260 details
RUNX3SMURF2BioGRID, HPRD15138260 details
RUNX3EZH2BioGRID20714105 details
RUNX3MDM2BioGRID19808967 details
RUNX3SIRT2BioGRID21511279 details
RUNX3RBPJBioGRID19800882 details
RUNX3PIN1BioGRID22580604 details
RUNX3PMLBioGRID15331439 details
RUNX3HDAC1BioGRID, HPRD15138260 details
RUNX3FANCD2BioGRID25066130 details
RUNX3FANCIBioGRID25066130 details
RUNX3DZIP3BioGRID29417297 details
RUNX3MEX3BBioGRID29417297 details
RUNX3HIF1ABioGRID23542169 details
RUNX3EGLN2BioGRID23542169 details
RUNX3EGLN1BioGRID23542169 details
RUNX3SUFUBioGRID31278361 details
RUNX3HDAC2HPRD15138260 details
RUNX3PHB2BioGRID, IntAct17353931 details
RUNX3CCND1IntAct24229708 details
RUNX3NANOGBioGRID26687479 details
RUNX3IKZF3BioGRID30760870 details
RUNX3IKZF1BioGRID30760870 details
RUNX3NHLRC2BioGRID30397336 details
RUNX3CICBioGRID29844126 details
RUNX3BRD4BioGRID32416067 details
RUNX3IL17AIntAct33179750 details
RUNX3XCL1IntAct33179750 details
RUNX3DDX58BioGRID32513696 details