Entity Details

Primary name ORMDL3
Entity type gene
Source Source Link

Details

PrimaryID94103
RefseqGene
SymbolORMDL3
NameORMDL sphingolipid biosynthesis regulator 3
Chromosome17
Location17q21.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-07-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsORML3_HUMAN

GO terms

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GOName
GO:0002903 negative regulation of B cell apoptotic process
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0006672 ceramide metabolic process
GO:0006686 sphingomyelin biosynthetic process
GO:0006940 regulation of smooth muscle contraction
GO:0010508 positive regulation of autophagy
GO:0016021 integral component of membrane
GO:0030667 secretory granule membrane
GO:0035339 SPOTS complex
GO:0035579 specific granule membrane
GO:0042552 myelination
GO:0043312 neutrophil degranulation
GO:0061744 motor behavior
GO:0090156 cellular sphingolipid homeostasis
GO:1900060 negative regulation of ceramide biosynthetic process
GO:1900182 positive regulation of protein localization to nucleus
GO:1904221 negative regulation of serine C-palmitoyltransferase activity

Diseases

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Interactions

39 interactions

InteractorPartnerSourcesPublicationsLink
ORMDL3EEF1A1BioGRID, HPRD, IntAct16169070 details
ORMDL3GPR101BioGRID, IntAct32296183 details
ORMDL3ELOVL4BioGRID, IntAct32296183 details
ORMDL3ARL13BBioGRID, IntAct32296183 details
ORMDL3ERGIC3BioGRID, IntAct32296183 details
ORMDL3SLC7A1BioGRID, IntAct32296183 details
ORMDL3GPR152BioGRID, IntAct32296183 details
ORMDL3SYT2BioGRID, IntAct32296183 details
ORMDL3HSD17B13BioGRID, IntAct32296183 details
ORMDL3C10orf67BioGRID, IntAct32296183 details
ORMDL3GET1BioGRID, IntAct32296183 details
ORMDL3MTIF3BioGRID, IntAct32296183 details
ORMDL3LEPROTL1BioGRID, IntAct32296183 details
ORMDL3TMEM237BioGRID, IntAct32296183 details
ORMDL3RETREG3BioGRID, IntAct32296183 details
ORMDL3RNF5BioGRID, IntAct32296183 details
ORMDL3COQ8ABioGRID, IntAct32296183 details
ORMDL3EBPBioGRID, IntAct32296183 details
ORMDL3FAM209ABioGRID, IntAct32296183 details
ORMDL3SLC10A1BioGRID, IntAct32296183 details
ORMDL3ROM1BioGRID, IntAct32296183 details
ORMDL3CERS3BioGRID, IntAct32296183 details
ORMDL3AQP6BioGRID, IntAct32296183 details
ORMDL3KCNK5BioGRID, IntAct32296183 details
ORMDL3REEP2BioGRID, IntAct32296183 details
ORMDL3SLC35C2BioGRID, IntAct32296183 details
ORMDL3LNX1BioGRID22889411 details
ORMDL3APPBioGRID21832049 details
ORMDL3PTPN11BioGRID27229929 details
ORMDL3LMNABioGRID24623722 details
ORMDL3SPTLC1BioGRID, DIP20182505 details
ORMDL3SYVN1BioGRID31477895 details
ORMDL3TCTN3BioGRID, IntAct26638075 details
ORMDL3SLC2A12BioGRID, IntAct28514442 details
ORMDL3SLC22A9BioGRID, IntAct28514442 details
ORMDL3SLC1A1BioGRID, IntAct28514442 details
ORMDL3SPRY4BioGRID, IntAct28514442 details
ORMDL3ELAVL1BioGRID19322201 details
ORMDL3HNRNPH1BioGRID26760575 details