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Entity Details
Primary name
IF_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
P27352
EntryName
IF_HUMAN
FullName
Cobalamin binding intrinsic factor
TaxID
9606
Evidence
evidence at protein level
Length
417
SequenceStatus
complete
DateCreated
1992-08-01
DateModified
2021-06-02
Ontological Relatives
Genes
CBLIF
GO terms
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GO
Name
GO:0005576
extracellular region
GO:0005615
extracellular space
GO:0005768
endosome
GO:0005902
microvillus
GO:0006824
cobalt ion transport
GO:0009235
cobalamin metabolic process
GO:0015889
cobalamin transport
GO:0016324
apical plasma membrane
GO:0031419
cobalamin binding
GO:0043202
lysosomal lumen
Subcellular Location
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Subcellular Location
Secreted
Domains
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Domain
Name
Category
Type
IPR002157
Cobalamin (vitamin B12)-binding protein
Family
Family
IPR027954
Domain of unknown function DUF4430
Domain
Domain
Diseases
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Disease ID
Source
Name
Description
261000
OMIM
Hereditary intrinsic factor deficiency (IFD)
Autosomal recessive disorder characterized by megaloblastic anemia.
The disease is caused by variants affecting the gene represented in this entry.
Drugs
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Drug
Name
Source
Type
DB00115
Cyanocobalamin
Drugbank
small molecule
Interactions
10 interactions
Interactor
Partner
Sources
Publications
Link
IF_HUMAN
FFAR2_HUMAN
BioGRID, IntAct
32296183
details
IF_HUMAN
SL7A1_HUMAN
BioGRID, IntAct
32296183
details
IF_HUMAN
CUBN_HUMAN
BioGRID, DIP, HPRD
20237569
9572993
details
IF_HUMAN
S22AN_HUMAN
BioGRID, IntAct
32296183
details
IF_HUMAN
S7A14_HUMAN
BioGRID, IntAct
32296183
details
IF_HUMAN
S13A4_HUMAN
BioGRID, IntAct
32296183
details
IF_HUMAN
TM237_HUMAN
BioGRID, IntAct
32296183
details
IF_HUMAN
CBL_HUMAN
BioGRID
11788601
details
IF_HUMAN
IF_HUMAN
DIP
17954916
details
IF_HUMAN
ATP4A_HUMAN
BioGRID
17255364
details
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