Entity Details

Primary name BANK1
Entity type gene
Source Source Link

Details

PrimaryID55024
RefseqGeneNG_015824
SymbolBANK1
NameB cell scaffold protein with ankyrin repeats 1
Chromosome4
Location4q24
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-07-03
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsBANK1_HUMAN

GO terms

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GOName
GO:0005102 signaling receptor binding
GO:0009617 response to bacterium
GO:0032715 negative regulation of interleukin-6 production
GO:0042113 B cell activation
GO:0043410 positive regulation of MAPK cascade
GO:0045947 negative regulation of translational initiation
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050869 negative regulation of B cell activation
GO:0051898 negative regulation of protein kinase B signaling
GO:1990782 protein tyrosine kinase binding

Diseases

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Disease IDSourceNameDescription
152700 OMIMSystemic lupus erythematosus (SLE)A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow. Disease susceptibility may be associated with variants affecting the gene represented in this entry.

Interactions

11 interactions