Entity Details

Primary name C1QA
Entity type gene
Source Source Link

Details

PrimaryID712
RefseqGeneNG_007282
SymbolC1QA
Namecomplement C1q A chain
Chromosome1
Location1p36.12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsC1QA_HUMAN

GO terms

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GOName
GO:0001540 amyloid-beta binding
GO:0001774 microglial cell activation
GO:0005576 extracellular region
GO:0005581 collagen trimer
GO:0005602 complement component C1 complex
GO:0006956 complement activation
GO:0006958 complement activation, classical pathway
GO:0007267 cell-cell signaling
GO:0007568 aging
GO:0010039 response to iron ion
GO:0016032 viral process
GO:0016322 neuron remodeling
GO:0030449 regulation of complement activation
GO:0045087 innate immune response
GO:0045202 synapse
GO:0048143 astrocyte activation
GO:0050808 synapse organization
GO:0062023 collagen-containing extracellular matrix
GO:0098794 postsynapse
GO:0098883 synapse pruning
GO:0150062 complement-mediated synapse pruning
GO:0150064 vertebrate eye-specific patterning
GO:1901216 positive regulation of neuron death

Diseases

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Disease IDSourceNameDescription
613652 OMIMComplement component C1q deficiency (C1QD)A disorder caused by impaired activation of the complement classical pathway. It generally leads to severe immune complex disease with features of systemic lupus erythematosus and glomerulonephritis. The disease is caused by variants affecting the gene represented in this entry.