Entity Details

Primary name ATCAY_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ86WG3
EntryNameATCAY_HUMAN
FullNameCaytaxin
TaxID9606
Evidenceevidence at protein level
Length371
SequenceStatuscomplete
DateCreated2003-10-31
DateModified2021-06-02

Ontological Relatives

GenesATCAY

GO terms

Show/Hide Table
GOName
GO:0004309 exopolyphosphatase activity
GO:0005737 cytoplasm
GO:0006798 polyphosphate catabolic process
GO:0006915 apoptotic process
GO:0019894 kinesin binding
GO:0030424 axon
GO:0030425 dendrite
GO:0030426 growth cone
GO:0031175 neuron projection development
GO:0031966 mitochondrial membrane
GO:0032880 regulation of protein localization
GO:0043005 neuron projection
GO:0044306 neuron projection terminus
GO:0045202 synapse
GO:0048311 mitochondrion distribution
GO:0048471 perinuclear region of cytoplasm
GO:0098793 presynapse
GO:2000212 negative regulation of glutamate metabolic process

Subcellular Location

Show/Hide Table
Subcellular Location
Cell junction
Cell projection
Cytoplasm
Mitochondrion

Domains

Show/Hide Table
DomainNameCategoryType
IPR001251 CRAL-TRIO lipid binding domainDomainDomain
IPR022181 Bcl2-/adenovirus E1B 19kDa-interacting protein 2FamilyFamily
IPR036865 CRAL-TRIO lipid binding domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table
Disease IDSourceNameDescription
601238 OMIMCerebellar ataxia, cayman type (ATCAY)Found in a population isolate on Grand Cayman Island and causes a marked psychomotor retardation and prominent nonprogressive cerebellar dysfunction including nystagmus, intention tremor, dysarthria, and wide-based ataxic gait. Hypotonia is present from early childhood. The disease is caused by variants affecting the gene represented in this entry.