Entity Details
Primary name |
P3H2_HUMAN |
Entity type |
UniProt |
Source |
Source Link |
Details
Accession | Q8IVL5 |
EntryName | P3H2_HUMAN |
FullName | Prolyl 3-hydroxylase 2 |
TaxID | 9606 |
Evidence | evidence at protein level |
Length | 708 |
SequenceStatus | complete |
DateCreated | 2006-06-27 |
DateModified | 2021-06-02 |
Subcellular Location
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Subcellular Location |
Endoplasmic reticulum |
Golgi apparatus |
Sarcoplasmic reticulum |
Domains
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Domain | Name | Category | Type |
IPR005123 | Oxoglutarate/iron-dependent dioxygenase | Domain | Domain |
IPR006620 | Prolyl 4-hydroxylase, alpha subunit | Domain | Domain |
IPR011990 | Tetratricopeptide-like helical domain superfamily | Family | Homologous superfamily |
IPR039575 | Prolyl 3-hydroxylase | Family | Family |
IPR039838 | Prolyl 3-hydroxylase 2 | Family | Family |
Diseases
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Disease ID | Source | Name | Description |
614292 | OMIM | Myopia, high, with cataract and vitreoretinal degeneration (MCVD) | A disorder characterized by severe myopia with variable expressivity of cataract and vitreoretinal degeneration. Some patients manifest lens subluxation, lens instability and retinal detachment. The disease is caused by variants affecting the gene represented in this entry. |
Drugs
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Drug | Name | Source | Type |
DB00126 | Ascorbic acid | Drugbank | small molecule |
DB00139 | Succinic acid | Drugbank | small molecule |
DB00172 | Proline | Drugbank | small molecule |
Interactions
0 interactions
Interactor | Partner | Sources | Publications | Link |