Entity Details

Primary name WDR36_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NI36
EntryNameWDR36_HUMAN
FullNameWD repeat-containing protein 36
TaxID9606
Evidenceevidence at protein level
Length951
SequenceStatuscomplete
DateCreated2004-04-26
DateModified2021-06-02

Ontological Relatives

GenesWDR36

GO terms

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GOName
GO:0003723 RNA binding
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0006364 rRNA processing
GO:0007601 visual perception
GO:0032040 small-subunit processome
GO:0034388 Pwp2p-containing subcomplex of 90S preribosome
GO:0050896 response to stimulus

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001680 WD40 repeatRepeatRepeat
IPR007319 Small-subunit processome, Utp21DomainDomain
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR019775 WD40 repeat, conserved siteSiteConserved site
IPR024977 Anaphase-promoting complex subunit 4, WD40 domainDomainDomain
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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Disease IDSourceNameDescription
609887 OMIMGlaucoma 1, open angle, G (GLC1G)A form of primary open angle glaucoma (POAG). POAG is characterized by a specific pattern of optic nerve and visual field defects. The angle of the anterior chamber of the eye is open, and usually the intraocular pressure is increased. However, glaucoma can occur at any intraocular pressure. The disease is generally asymptomatic until the late stages, by which time significant and irreversible optic nerve damage has already taken place. The disease is caused by variants affecting the gene represented in this entry.