Entity Details

Primary name SPF45_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96I25
EntryNameSPF45_HUMAN
FullNameSplicing factor 45
TaxID9606
Evidenceevidence at protein level
Length401
SequenceStatuscomplete
DateCreated2003-09-19
DateModified2021-06-02

Ontological Relatives

GenesRBM17

GO terms

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GOName
GO:0000380 alternative mRNA splicing, via spliceosome
GO:0000398 mRNA splicing, via spliceosome
GO:0003723 RNA binding
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0043484 regulation of RNA splicing

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000467 G-patch domainDomainDomain
IPR000504 RNA recognition motif domainDomainDomain
IPR003954 RNA recognition motif domain, eukaryoteDomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR034653 SPF45, RNA recognition motifDomainDomain
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily
IPR040052 Splicing factor 45FamilyFamily

Diseases

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Interactions

32 interactions

InteractorPartnerSourcesPublicationsLink
SPF45_HUMANSAT1_HUMANBioGRID, HPRD, IntAct, MINT16189514 21516116 25416956 31515488 32296183 details
SPF45_HUMANGOGA2_HUMANBioGRID, IntAct, MINT21516116 25416956 31515488 32296183 details
SPF45_HUMANCSK21_HUMANBioGRID, IntAct22113938 details
SPF45_HUMANSF3B1_HUMANBioGRID, DIP, IntAct, MINT17589525 22365833 28514442 details
SPF45_HUMANDHX15_HUMANBioGRID, IntAct, MINT22365833 25416956 29021621 32296183 details
SPF45_HUMANSUGP1_HUMANBioGRID, MINT22365833 details
SPF45_HUMANSR140_HUMANBioGRID, IntAct, MINT22365833 24981860 28514442 details
SPF45_HUMANSF01_HUMANBioGRID, DIP, IntAct, MINT17589525 22365833 26420826 32296183 details
SPF45_HUMANCWC15_HUMANBioGRID, MINT22365833 details
SPF45_HUMANS30BP_HUMANBioGRID, MINT22365833 details
SPF45_HUMANQRIC1_HUMANBioGRID, IntAct25416956 31515488 details
SPF45_HUMANCEP55_HUMANBioGRID, IntAct25416956 31515488 32296183 details
SPF45_HUMANFAM9B_HUMANBioGRID, IntAct25416956 details
SPF45_HUMANCCHCR_HUMANBioGRID, IntAct25416956 29892012 31515488 32296183 details
SPF45_HUMANPP12C_HUMANBioGRID, IntAct25416956 32296183 details
SPF45_HUMANIQCN_HUMANBioGRID, IntAct25416956 details
SPF45_HUMANHSF2B_HUMANBioGRID, IntAct32296183 details
SPF45_HUMANCC170_HUMANBioGRID, IntAct32296183 details
SPF45_HUMANU2AF2_HUMANDIP17589525 details
SPF45_HUMANATX1_HUMANDIP18337722 details
SPF45_HUMANCALR_HUMANIntAct32814053 details
SPF45_HUMANODO2_HUMANIntAct32814053 details
SPF45_HUMANPECA1_HUMANIntAct32814053 details
SPF45_HUMANWFS1_HUMANIntAct32814053 details
SPF45_HUMANNEK7_HUMANIntAct32814053 details
SPF45_HUMANHINFP_HUMANBioGRID17577209 details
SPF45_HUMANAPBB1_HUMANBioGRID16055720 details
SPF45_HUMANLNX2_HUMANBioGRID21516116 details
SPF45_HUMANOGT1_HUMANBioGRID32994395 details
SPF45_HUMANSF3A2_HUMANBioGRID, IntAct, MINT12234937 17332742 28514442 details
SPF45_HUMANSCHI1_HUMANIntAct20195357 details
SPF45_HUMANCDC5L_HUMANBioGRID, MINT20467437 29395067 details