Entity Details

Primary name CITE2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ99967
EntryNameCITE2_HUMAN
FullNameCbp/p300-interacting transactivator 2
TaxID9606
Evidenceevidence at protein level
Length270
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesCITED2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0001666 response to hypoxia
GO:0001889 liver development
GO:0003151 outflow tract morphogenesis
GO:0003156 regulation of animal organ formation
GO:0003682 chromatin binding
GO:0003713 transcription coactivator activity
GO:0003714 transcription corepressor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0007368 determination of left/right symmetry
GO:0007507 heart development
GO:0007530 sex determination
GO:0008283 cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0019904 protein domain specific binding
GO:0022409 positive regulation of cell-cell adhesion
GO:0030154 cell differentiation
GO:0030336 negative regulation of cell migration
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
GO:0032991 protein-containing complex
GO:0034405 response to fluid shear stress
GO:0035035 histone acetyltransferase binding
GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway
GO:0035802 adrenal cortex formation
GO:0043066 negative regulation of apoptotic process
GO:0043627 response to estrogen
GO:0045787 positive regulation of cell cycle
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048536 spleen development
GO:0050693 LBD domain binding
GO:0060412 ventricular septum morphogenesis
GO:0060971 embryonic heart tube left/right pattern formation
GO:0060972 left/right pattern formation
GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0070986 left/right axis specification
GO:1900164 nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
GO:2000020 positive regulation of male gonad development

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR007576 CITEDFamilyFamily

Diseases

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Disease IDSourceNameDescription
614433 OMIMAtrial septal defect 8 (ASD8)A congenital heart malformation characterized by incomplete closure of the wall between the atria resulting in blood flow from the left to the right atria. The disease is caused by variants affecting the gene represented in this entry.
614431 OMIMVentricular septal defect 2 (VSD2)A common form of congenital cardiovascular anomaly that may occur alone or in combination with other cardiac malformations. It can affect any portion of the ventricular septum, resulting in abnormal communications between the two lower chambers of the heart. Classification is based on location of the communication, such as perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular defect. Large defects that go unrepaired may give rise to cardiac enlargement, congestive heart failure, pulmonary hypertension, Eisenmenger's syndrome, delayed fetal brain development, arrhythmias, and even sudden cardiac death. The disease is caused by variants affecting the gene represented in this entry.