Entity Details

Primary name G6PC3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BUM1
EntryNameG6PC3_HUMAN
FullNameGlucose-6-phosphatase 3
TaxID9606
Evidenceevidence at protein level
Length346
SequenceStatuscomplete
DateCreated2008-05-20
DateModified2021-06-02

Ontological Relatives

GenesG6PC3

GO terms

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GOName
GO:0004346 glucose-6-phosphatase activity
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0006094 gluconeogenesis
GO:0015760 glucose-6-phosphate transport
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0051156 glucose 6-phosphate metabolic process

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidaseDomainDomain
IPR016275 Glucose-6-phosphataseFamilyFamily
IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamilyFamilyHomologous superfamily

Diseases

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Disease IDSourceNameDescription
612541 OMIMNeutropenia, severe congenital 4, autosomal recessive (SCN4)A disorder of hematopoiesis characterized by maturation arrest of granulopoiesis at the level of promyelocytes with peripheral blood absolute neutrophil counts below 0.5 x 10(9)/l and early onset of severe bacterial infections. The disease is caused by variants affecting the gene represented in this entry.
612541 OMIMNeutropenia, severe congenital 4, autosomal recessive (SCN4)A disorder of hematopoiesis characterized by maturation arrest of granulopoiesis at the level of promyelocytes with peripheral blood absolute neutrophil counts below 0.5 x 10(9)/l and early onset of severe bacterial infections. The disease is caused by variants affecting the gene represented in this entry.

Interactions

4 interactions