Entity Details
| Primary name |
SYCM_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | Q9HA77 |
| EntryName | SYCM_HUMAN |
| FullName | Probable cysteine--tRNA ligase, mitochondrial |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 564 |
| SequenceStatus | complete |
| DateCreated | 2006-10-03 |
| DateModified | 2021-06-02 |
Subcellular Location
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| Subcellular Location |
| Mitochondrion matrix |
Domains
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| Domain | Name | Category | Type |
| IPR009080 | Aminoacyl-tRNA synthetase, class Ia, anticodon-binding | Family | Homologous superfamily |
| IPR014729 | Rossmann-like alpha/beta/alpha sandwich fold | Family | Homologous superfamily |
| IPR015803 | Cysteine-tRNA ligase | Family | Family |
| IPR024909 | Cysteinyl-tRNA synthetase/mycothiol ligase | Family | Family |
| IPR032678 | tRNA synthetases class I, catalytic domain | Domain | Domain |
Diseases
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| Disease ID | Source | Name | Description |
| 616672 | OMIM | Combined oxidative phosphorylation deficiency 27 (COXPD27) | An autosomal recessive mitochondrial disorder characterized by multiple mitochondrial respiratory-chain-complex deficiencies causing neurological regression, progressive cognitive decline, complex movement disorder, epileptic encephalopathy, progressive spastic tetraparesis, and progressive impairment of vision and hearing. The disease is caused by variants affecting the gene represented in this entry. |
Drugs
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| Drug | Name | Source | Type |
| DB00151 | Cysteine | Drugbank | small molecule |
Interactions
1 interaction