Entity Details

Primary name TMM98_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y2Y6
EntryNameTMM98_HUMAN
FullNameTransmembrane protein 98
TaxID9606
Evidenceevidence at protein level
Length226
SequenceStatuscomplete
DateCreated2006-10-03
DateModified2021-06-02

Ontological Relatives

GenesTMEM98

GO terms

Show/Hide Table
GOName
GO:0005615 extracellular space
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0010955 negative regulation of protein processing
GO:0016021 integral component of membrane
GO:0031642 negative regulation of myelination
GO:0045063 T-helper 1 cell differentiation
GO:0048715 negative regulation of oligodendrocyte differentiation
GO:0070062 extracellular exosome
GO:1900181 negative regulation of protein localization to nucleus

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane
Endoplasmic reticulum membrane
Secreted

Domains

Show/Hide Table
DomainNameCategoryType
IPR029668 Transmembrane protein 98FamilyFamily

Diseases

Show/Hide Table
Disease IDSourceNameDescription
615972 OMIMNanophthalmos 4 (NNO4)A rare disorder of eye development characterized by extreme hyperopia (farsightedness) and small functional eyes. The cornea and lens are normal in size and shape. Hyperopia occurs because insufficient growth along the visual axis places these lensing components too close to the retina. Nanophthalmic eyes show considerable thickening of both the choroidal vascular bed and scleral coat, which provide nutritive and structural support for the retina. The disease is caused by variants affecting the gene represented in this entry.