Entity Details

Primary name FZD2
Entity type gene
Source Source Link

Details

PrimaryID2535
RefseqGene
SymbolFZD2
Namefrizzled class receptor 2
Chromosome17
Location17q21.31
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsFZD2_HUMAN

GO terms

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GOName
GO:0003149 membranous septum morphogenesis
GO:0003150 muscular septum morphogenesis
GO:0003151 outflow tract morphogenesis
GO:0004930 G protein-coupled receptor activity
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0007223 Wnt signaling pathway, calcium modulating pathway
GO:0007608 sensory perception of smell
GO:0016021 integral component of membrane
GO:0016055 Wnt signaling pathway
GO:0017147 Wnt-protein binding
GO:0030165 PDZ domain binding
GO:0030182 neuron differentiation
GO:0030669 clathrin-coated endocytic vesicle membrane
GO:0030855 epithelial cell differentiation
GO:0042813 Wnt-activated receptor activity
GO:0045893 positive regulation of transcription, DNA-templated
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0060022 hard palate development
GO:0060070 canonical Wnt signaling pathway
GO:0060071 Wnt signaling pathway, planar cell polarity pathway
GO:0060119 inner ear receptor cell development
GO:0090103 cochlea morphogenesis
GO:0090179 planar cell polarity pathway involved in neural tube closure
GO:1904886 beta-catenin destruction complex disassembly

Diseases

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Disease IDSourceNameDescription
164745 OMIMOmodysplasia 2 (OMOD2)A rare autosomal dominant skeletal dysplasia characterized by short humeri, radial head dislocation, short first metacarpals, facial dysmorphism and genitourinary anomalies. The disease is caused by variants affecting the gene represented in this entry.