Entity Details

Primary name HBG2
Entity type gene
Source Source Link

Details

PrimaryID3048
RefseqGeneNG_000007
SymbolHBG2
Namehemoglobin subunit gamma 2
Chromosome11
Location11p15.4
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsHBG2_HUMAN

GO terms

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GOName
GO:0005344 oxygen carrier activity
GO:0005829 cytosol
GO:0005833 hemoglobin complex
GO:0007596 blood coagulation
GO:0019825 oxygen binding
GO:0020037 heme binding
GO:0031721 hemoglobin alpha binding
GO:0031838 haptoglobin-hemoglobin complex
GO:0042744 hydrogen peroxide catabolic process
GO:0043177 organic acid binding
GO:0046872 metal ion binding
GO:0072562 blood microparticle
GO:0098869 cellular oxidant detoxification

Diseases

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Disease IDSourceNameDescription
613977 OMIMCyanosis transient neonatal (TNCY)A disorder characterized by cyanosis in the fetus and neonate, due to a defect in the fetal hemoglobin chain which has reduced affinity for oxygen. Some patients develop anemia resulting from increased destruction of red cells containing abnormal or unstable hemoglobin. The cyanosis resolves spontaneously by 5 to 6 months of age or earlier, as the adult beta-globin chain is produced and replaces the fetal gamma-globin chain. The disease is caused by variants affecting the gene represented in this entry.

Interactions

19 interactions